CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Operating activities
Net loss	$ (63,005)	$ (51,823)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	3,200	2,817
Depreciation	1,462	1,413
Non-cash lease expense	1,828
(Gain) loss on disposal of property and equipment		(35)
Amortization (accretion) of available-for-sale securities	235	987
Changes in operating assets and liabilities:
Accounts receivable from related party	11,402	(10,165)
Prepaid expenses and other current assets	611	(1,761)
Accounts payable	(3,128)	1,881
Accrued expenses and other current liabilities	941	3,438
Deferred rent and lease incentive		(607)
Deferred collaboration liability	(8,401)	9,404
Operating lease liability	(2,355)
Other long-term liabilities	312	1,301
Net cash used in operating activities	(56,898)	(43,150)
Investing activities
Purchases of available-for-sale securities	(97,513)	(197,457)
Proceeds from maturities of available-for-sale securities	153,073	97,068
Proceeds from sale of property and equipment		139
Purchases of property and equipment	(463)	(745)
Net cash provided by (used in) investing activities	55,097	(100,995)
Financing activities
Proceeds from the issuance of Series D convertible preferred stock		27,400
Proceeds from issuance of common stock upon completion of initial public offering net of commissions and underwriting discounts		128,240
Payment of initial public offering costs		(3,255)
Proceeds from the exercise of stock options		319
Principal payments on finance lease liability	(213)	(193)
Repurchases of early exercised restricted stock		(1)
Net cash (used in) provided by financing activities	(213)	152,510
Net (decrease) increase in cash, cash equivalents and restricted cash	(2,014)	8,365
Cash, cash equivalents and restricted cash at beginning of period	37,583	29,218
Cash, cash equivalents and restricted cash at end of period	35,569	37,583
Supplemental cash flow information:
Cash paid for interest for finance lease	14	34
Supplemental disclosure of non-cash activities:
Operating lease right-of-use asset recognized upon adoption of ASC 842	11,485
Property and equipment purchases in accounts payable and accrued expenses	$ 197	46
Vesting of early exercised restricted stock		$ 18