Net Loss Per Common Share (Tables)

9 Months Ended

Sep. 30, 2016

Net Loss Per Common Share

Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding

	Three Months Ended		Nine Months Ended
	September 30,		September 30,
	2016	2015	2016	2015
Stock options	2,567,017	1,583,521	2,567,017	1,583,521
Stock warrants	310,220	326,553	310,220	326,553
Unvested restricted stock units	57,500	—	57,500	—
Unvested restricted common stock	—	1,750,794	—	1,750,794
	2,934,737	3,660,868	2,934,737	3,660,868

Summary of the basic and diluted net loss per common share

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Numerator:
Net loss and comprehensive loss	$	(21,081,808	)	$	(9,940,658	)	$	(57,636,873	)	$	(25,313,037	)
Denominator:
Weighted-average basic and diluted common shares	24,166,113			7,504,148			20,958,421			7,042,977
Basic and diluted net loss per common share	$	(0.87	)	$	(1.32	)	$	(2.75	)	$	(3.59	)