Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)	3 Months Ended	6 Months Ended
Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Operating expenses:
General and administrative	$ 5,418,266	$ 2,268,521	$ 10,242,180	$ 2,911,156
Research and development	10,379,521	7,654,839	26,444,610	12,466,864
Total operating expenses	15,797,787	9,923,360	36,686,790	15,378,020
Loss from operations	(15,797,787)	(9,923,360)	(36,686,790)	(15,378,020)
Interest income	78,829	4,185	131,725	5,641
Net loss	(15,718,958)	(9,919,175)	(36,555,065)	(15,372,379)
Comprehensive loss	$ (15,718,958)	$ (9,919,175)	$ (36,555,065)	$ (15,372,379)
Basic and diluted net loss per common share (in dollars per share)	$ (0.68)	$ (1.41)	$ (1.84)	$ (3.05)
Weighted-average basic and diluted common shares outstanding (in shares)	23,013,838	7,030,976	19,876,850	5,045,211

Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners.

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