Quarterly Financial Information (Unaudited)

12 Months Ended

Dec. 31, 2016

Quarterly Financial Information (Unaudited)

Quarterly Financial Information (Unaudited)

17. Quarterly Financial Information (Unaudited)

        Summarized quarterly financial information for each of the years ended December 31, 2016 and 2015 are as follows:

	Quarter Ended
	December 31, 2016			September 30, 2016			June 30, 2016			March 31, 2016
Revenue	$	—		$	—		$	—		$	—
Loss from operations	$	(25,547,384	)	$	(21,180,396	)	$	(15,797,787	)	$	(20,889,002	)
Interest income	$	172,453		$	98,588		$	78,829		$	52,895
Net loss and comprehensive loss	$	(25,374,931	)	$	(21,081,808	)	$	(15,718,958	)	$	(20,836,107	)
Basic and diluted net loss per common share	$	(0.92	)	$	(0.87	)	$	(0.68	)	$	(1.24	)
Weighted-average basic and diluted common shares outstanding		27,678,348			24,166,113			23,013,838			16,774,718

	Quarter Ended
	December 31, 2015			September 30, 2015			June 30, 2015			March 31, 2015
Revenue	$	—		$	—		$	—		$	—
Loss from continuing operations	$	(13,165,526	)	$	(10,029,427	)	$	(9,923,360	)	$	(5,454,659	)
Other income	$	4,719		$	88,769		$	4,185		$	1,455
Net loss	$	(13,160,807	)	$	(9,940,658	)	$	(9,919,175	)	$	(5,453,204	)
Basic and diluted net loss per common share	$	(1.82	)	$	(1.32	)	$	(1.41	)	$	(0.79	)
Weighted-average basic and diluted common shares outstanding		7,226,122			7,504,148			7,030,976			6,895,185