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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 71 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Mar. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (46,205) $ (31,806)  
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 1,591 1,541  
Equity-based compensation 6,424 4,157  
Amortization/accretion of investment premiums/discounts 1,209 (200)  
Changes in operating assets and liabilities:      
Accounts receivable 1,177 (8,748)  
Prepaid expenses and other current assets (5,448) (448)  
Operating right-of-use assets 1,596 1,566  
Other assets (255) 97  
Accounts payable (917) (370)  
Accrued expenses (4,588) 177  
Deferred revenue (5,558) (3,151)  
Operating lease liabilities (1,402) (1,360)  
Net cash used in operating activities (52,376) (38,545)  
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of property and equipment (2,412) (845)  
Purchases of marketable securities (148,330) (31,207)  
Maturities of marketable securities 125,200 89,500  
Net cash (used in) provided by investing activities (25,542) 57,448  
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of common stock through at-the-market offerings, net of issuance costs     $ 1,165,300
Proceeds from options exercised 13,340 336  
Net cash provided by financing activities 58,595 4,864  
Net (decrease) increase in cash and cash equivalents and restricted cash and cash equivalents (19,323) 23,767  
Cash and cash equivalents and restricted cash and cash equivalents, beginning of period 164,606 57,226  
Cash and cash equivalents and restricted cash and cash equivalents, end of period 145,283 80,993 145,283
Reconciliation of cash and cash equivalents and restricted cash and cash equivalents to condensed consolidated balance sheet:      
Cash and cash equivalents 141,538 80,993 141,538
Restricted cash and cash equivalents, included in prepaids and other current assets and other assets 3,745   3,745
Cash and cash equivalents and restricted cash and cash equivalents, end of period 145,283 80,993 145,283
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:      
Purchases of property and equipment unpaid at period end 901 750  
Right-of-use assets acquired under operating leases 40,394 7,347  
Proceeds from at-the-market offerings unpaid at period end   551  
At The Market Offerings [Member]      
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of common stock through at-the-market offerings, net of issuance costs $ 45,255 $ 4,528 $ 196,500