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Overview and Basis of Presentation - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 71 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Mar. 31, 2021
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     $ 1,165,300
Proceeds from issuance of convertible preferred stock     85,000
Collaborative Arrangement [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     275,000
Initial Public Offering and Concurrent Private Placements [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     170,500
Follow-on public Offerings [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     438,300
At The Market Offerings [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering $ 45,255 $ 4,528 $ 196,500