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Overview and Basis of Presentation - Additional Information (Detail) - USD ($)
$ in Thousands
9 Months Ended 77 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     $ 893,600
Proceeds from issuance of convertible preferred stock     85,000
Collaborative Arrangement [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     272,600
Initial Public Offering and Concurrent Private Placements [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering     170,500
Follow-on public Offerings [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering $ 107,732   249,100
At-the-Market Offerings [Member]      
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]      
Proceeds from common stock offering $ 14,722 $ 54,120 $ 116,400