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Consolidated Statements of Operations - USD ($)
shares in Thousands
3 Months Ended 8 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]                      
Collaboration revenue $ 5,627,000 $ 4,869,000 $ 4,206,000 $ 1,777,000 $ 1,693,000 $ 1,688,000 $ 1,377,000 $ 1,286,000   $ 16,479,000 $ 6,044,000
Operating expenses:                      
Research and development 11,331,000 7,861,000 7,423,000 5,225,000 4,375,000 3,458,000 1,966,000 1,371,000 $ 1,105,000 31,840,000 11,170,000
In-process research and development                 6,055,000    
General and administrative 5,118,000 4,705,000 3,729,000 3,246,000 2,809,000 1,531,000 2,833,000 1,110,000 2,379,000 16,798,000 8,283,000
Total operating expenses 16,449,000 12,566,000 11,152,000 8,471,000 7,184,000 4,989,000 4,799,000 2,481,000 9,539,000 48,638,000 19,453,000
Operating loss (10,822,000) (7,697,000) (6,946,000) (6,694,000) (5,491,000) (3,301,000) (3,422,000) (1,195,000) (9,539,000) (32,159,000) (13,409,000)
Interest income 259,000 215,000 46,000 5,000           525,000  
Loss before income taxes (10,563,000) (7,482,000) (6,900,000) (6,689,000) (5,491,000) (3,301,000) (3,422,000) (1,195,000) (9,539,000) (31,634,000) (13,409,000)
Benefit from income taxes         246,000 282,000 382,000 102,000   0 1,012,000
Net loss $ (10,563,000) $ (7,482,000) $ (6,900,000) $ (6,689,000) $ (5,245,000) $ (3,019,000) $ (3,040,000) $ (1,093,000) $ (9,539,000) $ (31,634,000) $ (12,397,000)
Net loss per share or common unit, basic and diluted $ (0.31) $ (0.22) $ (0.36) $ (9.89) $ (9.57) $ (10.27) $ (2.37) $ (0.85) $ (11.55) $ (1.42) $ (51.02)
Weighted average shares or common units outstanding, basic and diluted 34,507 34,316 19,121 676 548 294 1,284 1,284 826 22,222 243