Leases - Additional Information (Detail) $ in Thousands	1 Months Ended			12 Months Ended
	Nov. 30, 2024	Jan. 31, 2023 ft²	Feb. 28, 2022 ft²	Dec. 31, 2024 USD ($) ft²	Dec. 31, 2023 USD ($)
Lessee Lease Description [Line Items]
Operating lease right-of-use assets				$ 219,292	$ 115,375
Lease liability				210,198
Prepaid Rent				$ 4,410	$ 1,190
Albany Lease [Member]
Lessee Lease Description [Line Items]
Operating lease, existence of option to extend				true
840 Winter Street Lease [Member]
Lessee Lease Description [Line Items]
Area of space leased | ft²			140,000
Operating lease, description			In February 2022 and subsequently amended in June 2023, the Company entered into an agreement to lease approximately 140,000 square feet of office, general laboratory and manufacturing space at 840 Winter Street in Waltham
Operating lease, options to extend	The Company had options to extend the lease for two five-year terms, which were not reasonably certain of exercise as of the commencement date.
Operating lease right-of-use assets				$ 125,700
Operating lease, existence of option to extend	true
Lease liability				$ 113,100
Operating lease, term of contract				12 years
Prepaid Rent				$ 12,600
Initial lease term expiration period				2036-09
Fixed Rate				3.00%
Cambridge [Member]
Lessee Lease Description [Line Items]
Area of space leased | ft²		13,000		230,000