Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	At The Market Offerings [Member] 2019 Sales Agreement [Member]	At The Market Offerings [Member] 2022 Sales Agreement [Member]	Follow-on Offering [Member]	Common Stock	Common Stock At The Market Offerings [Member] 2019 Sales Agreement [Member]	Common Stock At The Market Offerings [Member] 2022 Sales Agreement [Member]	Common Stock Follow-on Offering [Member]	Additional Paid-In Capital	Additional Paid-In Capital At The Market Offerings [Member] 2019 Sales Agreement [Member]	Additional Paid-In Capital At The Market Offerings [Member] 2022 Sales Agreement [Member]	Additional Paid-In Capital Follow-on Offering [Member]	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2021	$ 1,040,244				$ 7				$ 1,745,870				$ (2,632)	$ (703,001)
Beginning balance, shares at Dec. 31, 2021					74,485,883
Issuance of common stock		$ 38,886	$ 189,011	$ 337,892		$ 1		$ 1		$ 38,885	$ 189,011	$ 337,891
Issuance of common stock, shares						579,788	3,395,339	7,532,751
Exercise of stock options	14,517								14,517
Exercise of stock options, shares					883,954
Vesting of restricted stock units, shares					147,674
Issuance of shares under employee stock purchase plan	2,649								2,649
Issuance of shares under employee stock purchase plan, shares					77,618
Stock-based compensation	91,400								91,400
Other comprehensive income (loss) - unrealized gain (loss) on marketable securities	(1,637)												(1,637)
Other comprehensive income (loss) - unrealized gain (loss) on equity method investment	(3,192)												(3,192)
Net Income (Loss)	(474,186)													(474,186)
Ending balance at Dec. 31, 2022	1,235,584				$ 9				2,420,223				(7,461)	(1,177,187)
Ending balance, shares at Dec. 31, 2022					87,103,007
Issuance of common stock			121,870								121,870
Issuance of common stock, shares							4,122,824
Contingent consideration paid, shares					567,045
Contingent consideration paid	24,126								24,126
Exercise of stock options	6,599								6,599
Exercise of stock options, shares					385,130
Vesting of restricted stock units, shares					677,055
Issuance of shares under employee stock purchase plan	3,929								3,929
Issuance of shares under employee stock purchase plan, shares					142,097
Stock-based compensation	134,050								134,050
Other comprehensive income (loss) - unrealized gain (loss) on marketable securities	3,635												3,635
Other comprehensive income (loss) - unrealized gain (loss) on equity method investment	1,568												1,568
Net Income (Loss)	(481,192)													(481,192)
Ending balance at Dec. 31, 2023	$ 1,050,169				$ 9				2,710,797				(2,258)	(1,658,379)
Ending balance, shares at Dec. 31, 2023	92,997,158				92,997,158
Issuance of common stock			$ 174,824				$ 1				$ 174,823
Issuance of common stock, shares							7,004,370
Exercise of stock options	$ 5,862								5,862
Exercise of stock options, shares	373,807				373,807
Vesting of restricted stock units, shares					1,433,669
Issuance of shares under employee stock purchase plan	$ 2,986								2,986
Issuance of shares under employee stock purchase plan, shares					220,590
Stock-based compensation	154,273								154,273
Other comprehensive income (loss) - unrealized gain (loss) on marketable securities	731												731
Other comprehensive income (loss) - unrealized gain (loss) on equity method investment	2,132												2,132
Net Income (Loss)	(519,021)													(519,021)
Ending balance at Dec. 31, 2024	$ 871,956				$ 10				$ 3,048,741				$ 605	$ (2,177,400)
Ending balance, shares at Dec. 31, 2024	102,029,594				102,029,594