Fair Value Measurements - Additional information (Detail) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Risk-free interest rate	4.20%	4.40%	1.90%
Research milestone payments	$ 25.0
Cash Member
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Research milestone payments	0.9
AvenCell [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investment Owned, Fair Value	$ 7.9	$ 11.8
Indicated equity volatility	95.00%
Risk-free interest rate	3.90%
Sparing Vision [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Investment Owned, Fair Value	$ 14.6	$ 14.8