Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Income Statement [Abstract]
Collaboration revenue	$ 57,877	$ 36,275	$ 52,121
Type of Revenue [Extensible List]	us-gaap:LicenseAndServiceMember	us-gaap:LicenseAndServiceMember	us-gaap:LicenseAndServiceMember
Operating expenses:
Research and development	$ 466,311	$ 435,069	$ 419,979
General and administrative	125,829	116,497	90,306
Total operating expenses	592,140	551,566	510,285
Operating loss	(534,263)	(515,291)	(458,164)
Other income (expense), net:
Interest income	47,807	49,832	8,542
Change in fair value of investments, net	(32,565)	0	0
Loss from equity method investment	0	(15,633)	(11,079)
Change in fair value of contingent consideration	0	(100)	(13,485)
Total other income (expense), net	15,242	34,099	(16,022)
Net loss	$ (519,021)	$ (481,192)	$ (474,186)
Net loss per share, basic	$ (5.25)	$ (5.42)	$ (6.16)
Net loss per share, diluted	$ (5.25)	$ (5.42)	$ (6.16)
Weighted average shares outstanding, basic	98,849	88,770	76,972
Weighted average shares outstanding, diluted	98,849	88,770	76,972
Other comprehensive loss:
Unrealized gain (loss) on marketable securities	$ 731	$ 3,635	$ (1,637)
Other comprehensive gain (loss) from equity method investment	0	1,568	(3,192)
Comprehensive loss	$ (518,290)	$ (475,989)	$ (479,015)