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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Income Statement [Abstract]        
Collaboration revenue $ 9,111 $ 11,992 $ 45,003 $ 38,192
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:        
Research and development $ 123,380 $ 113,696 $ 349,434 $ 326,088
General and administrative 30,501 29,403 93,385 87,503
Total operating expenses 153,881 143,099 442,819 413,591
Operating loss (144,770) (131,107) (397,816) (375,399)
Other income (expense), net:        
Interest income 12,122 12,740 37,176 37,373
Change in fair value of investments, net (3,064) 0 (29,483) 0
Loss from equity method investment 0 (3,857) 0 (10,905)
Change in fair value of contingent consideration 0 0 0 (100)
Total other income , net 9,058 8,883 7,693 26,368
Net loss $ (135,712) $ (122,224) $ (390,123) $ (349,031)
Net loss per share, basic $ (1.34) $ (1.38) $ (3.99) $ (3.96)
Net loss per share, diluted $ (1.34) $ (1.38) $ (3.99) $ (3.96)
Weighted average shares outstanding, basic 101,002 88,645 97,842 88,204
Weighted average shares outstanding, diluted 101,002 88,645 97,842 88,204
Other comprehensive income:        
Unrealized gain on marketable securities $ 4,452 $ 142 $ 3,423 $ 1,649
Other comprehensive gain from equity method investment 0 154 0 2,240
Comprehensive loss $ (131,260) $ (121,928) $ (386,700) $ (345,142)