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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Income Statement [Abstract]        
Collaboration revenue $ 6,957 $ 13,594 $ 35,892 $ 26,200
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:        
Research and development $ 114,207 $ 115,276 $ 226,054 $ 212,392
General and administrative 31,793 30,652 62,884 58,100
Total operating expenses 146,000 145,928 288,938 270,492
Operating loss (139,043) (132,334) (253,046) (244,292)
Other (expense) income, net:        
Interest income 12,422 12,653 25,054 24,633
Change in fair value of investments, net (20,354) 0 (26,419) 0
Loss from equity method investment 0 (4,000) 0 (7,048)
Change in fair value of contingent consideration 0 0 0 (100)
Total other (expense) income , net (7,932) 8,653 (1,365) 17,485
Net loss $ (146,975) $ (123,681) $ (254,411) $ (226,807)
Net loss per share, basic $ (1.52) $ (1.4) $ (2.64) $ (2.58)
Net loss per share, diluted $ (1.52) $ (1.4) $ (2.64) $ (2.58)
Weighted average shares outstanding, basic 96,975 88,185 96,238 87,979
Weighted average shares outstanding, diluted 96,975 88,185 96,238 87,979
Other comprehensive (loss) gain:        
Unrealized (loss) gain on marketable securities $ (208) $ (1,482) $ (1,029) $ 1,507
Other comprehensive gain - equity method investment 0 292 0 2,086
Comprehensive loss $ (147,183) $ (124,871) $ (255,440) $ (223,214)