EXHIBIT 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in Registration Statement No. 333-275740 on Form S-3 and Registration Statement Nos. 333-211200, 333-218511, 333-229900, 333-236714, 333-253562, 333-262997, and 333-269947 on Form S-8 of our reports dated February 22, 2024, relating to the financial statements of Intellia Therapeutics, Inc., and the effectiveness of Intellia Therapeutics, Inc.’s internal control over financial reporting appearing in this Annual Report on Form 10-K for the year ended December 31, 2023.

/s/ Deloitte & Touche LLP

Boston, Massachusetts

February 22, 2024