Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	2022 Sales Agreement [Member]	Follow On Public Offering	At The Market Offerings	At The Market Offerings 2019 Sales Agreement [Member]	At The Market Offerings 2022 Sales Agreement [Member]	Common Stock	Common Stock Follow On Public Offering	Common Stock At The Market Offerings	Common Stock At The Market Offerings 2019 Sales Agreement [Member]	Common Stock At The Market Offerings 2022 Sales Agreement [Member]	Additional Paid-In Capital	Additional Paid-In Capital Follow On Public Offering	Additional Paid-In Capital At The Market Offerings	Additional Paid-In Capital At The Market Offerings 2019 Sales Agreement [Member]	Additional Paid-In Capital At The Market Offerings 2022 Sales Agreement [Member]	Accumulated Other Comprehensive Income	Retained Earnings
Beginning balance at Dec. 31, 2020	$ 527,072						$ 7					$ 962,173					$ 1	$ (435,109)
Beginning balance, shares at Dec. 31, 2020							66,234,056
Issuance of common stock			$ 648,315	$ 45,255									$ 648,315	$ 45,255
Issuance of common stock, shares								4,758,620	641,709
Exercise of stock options	41,094											41,094
Exercise of stock options, shares							2,700,886
Vesting of restricted stock units, shares							119,715
Issuance of shares under employee stock purchase plan	2,024											2,024
Issuance of shares under employee stock purchase plan, shares							30,897
Stock-based compensation	47,009											47,009
Other comprehensive loss - unrealized gain (loss) on marketable securities	(2,126)																(2,126)
Other comprehensive loss - equity method investment	(507)																(507)
Net Income (Loss)	(267,892)																	(267,892)
Ending balance at Dec. 31, 2021	1,040,244						$ 7					1,745,870					(2,632)	(703,001)
Ending balance, shares at Dec. 31, 2021							74,485,883
Issuance of common stock			$ 337,892		$ 38,886	$ 189,011		$ 1		$ 1			$ 337,891		$ 38,885	$ 189,011
Issuance of common stock, shares		3,395,339						7,532,751		579,788	3,395,339
Exercise of stock options	14,517											14,517
Exercise of stock options, shares							883,954
Vesting of restricted stock units, shares							147,674
Issuance of shares under employee stock purchase plan	2,649											2,649
Issuance of shares under employee stock purchase plan, shares							77,618
Stock-based compensation	91,400											91,400
Other comprehensive loss - unrealized gain (loss) on marketable securities	(1,637)																(1,637)
Other comprehensive loss - equity method investment	(3,192)																(3,192)
Net Income (Loss)	(474,186)																	(474,186)
Ending balance at Dec. 31, 2022	$ 1,235,584						$ 9					2,420,223					(7,461)	(1,177,187)
Ending balance, shares at Dec. 31, 2022	87,103,007						87,103,007
Issuance of common stock						$ 121,870										$ 121,870
Issuance of common stock, shares		4,122,824									4,122,824
Contingent consideration paid, shares							567,045
Contingent consideration paid	$ 24,126											24,126
Exercise of stock options	$ 6,599											6,599
Exercise of stock options, shares	385,130						385,130
Vesting of restricted stock units, shares							677,055
Issuance of shares under employee stock purchase plan	$ 3,929											3,929
Issuance of shares under employee stock purchase plan, shares							142,097
Stock-based compensation	134,050											134,050
Other comprehensive loss - unrealized gain (loss) on marketable securities	3,635																3,635
Other comprehensive loss - equity method investment	1,568																1,568
Net Income (Loss)	(481,192)																	(481,192)
Ending balance at Dec. 31, 2023	$ 1,050,169						$ 9					$ 2,710,797					$ (2,258)	$ (1,658,379)
Ending balance, shares at Dec. 31, 2023	92,997,158						92,997,158