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Income Taxes - Schedule of Reconciliation of the Federal Statutory Income Tax Rate and the Company's Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Disclosure [Abstract]      
Federal statutory income tax rate (21.00%) (21.00%) (21.00%)
State income taxes (8.60%) (8.30%) (16.60%)
Research and development tax credits (6.90%) (5.30%) (8.70%)
Stock-based compensation 1.60% (0.10%) (16.80%)
Non-deductible officers' compensation 0.00% 0.10% 0.20%
In-process research and development 0.00% 2.50% 0.00%
Change in valuation allowance 34.90% 32.10% 62.90%
Effective income tax rate 0.00% 0.00% 0.00%