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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Statement [Abstract]      
Collaboration revenue $ 36,275 $ 52,121 $ 33,053
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:      
Research and development $ 435,069 $ 419,979 $ 229,807
General and administrative 116,497 90,306 71,096
Total operating expenses 551,566 510,285 300,903
Operating loss (515,291) (458,164) (267,850)
Other income (expense), net:      
Interest income 49,832 8,542 1,283
Loss from equity method investments (15,633) (11,079) (1,325)
Change in fair value of contingent consideration (100) (13,485) 0
Total other income (expense), net 34,099 (16,022) (42)
Net loss $ (481,192) $ (474,186) $ (267,892)
Net Loss Per Share, Basic $ (5.42) $ (6.16) $ (3.78)
Net Loss Per Share, Diluted $ (5.42) $ (6.16) $ (3.78)
Weighted average shares outstanding, basic 88,770 76,972 70,894
Weighted average shares outstanding, diluted 88,770 76,972 70,894
Other comprehensive loss:      
Unrealized gain (loss) on marketable securities $ 3,635 $ (1,637) $ (2,126)
Other comprehensive gain (loss) from equity method investment 1,568 (3,192) (507)
Comprehensive loss $ (475,989) $ (479,015) $ (270,525)