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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Income Statement [Abstract]        
Collaboration revenue $ 13,594 $ 14,030 $ 26,200 $ 25,282
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:        
Research and development $ 115,276 $ 90,199 $ 212,392 $ 223,294
General and administrative 30,652 22,132 58,100 44,535
Total operating expenses 145,928 112,331 270,492 267,829
Operating loss (132,334) (98,301) (244,292) (242,547)
Other income (expense), net:        
Interest income 12,653 703 24,633 1,243
Loss from equity method investment (4,000) (3,252) (7,048) (5,997)
Change in fair value of contingent consideration 0 172 (100) (249)
Total other income (expense), net 8,653 (2,377) 17,485 (5,003)
Net loss $ (123,681) $ (100,678) $ (226,807) $ (247,550)
Net loss per share, basic $ (1.4) $ (1.33) $ (2.58) $ (3.29)
Net loss per share, diluted $ (1.4) $ (1.33) $ (2.58) $ (3.29)
Weighted average shares outstanding, basic 88,185 75,823 87,979 75,282
Weighted average shares outstanding, diluted 88,185 75,823 87,979 75,282
Other comprehensive loss:        
Unrealized (loss) gain on marketable securities $ (1,482) $ (932) $ 1,507 $ (6,060)
Other comprehensive gain (loss) from equity method investment 292 (560) 2,086 (862)
Comprehensive loss $ (124,871) $ (102,170) $ (223,214) $ (254,472)