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Stockholders’ Equity (Tables)
9 Months Ended
Sep. 30, 2021
Equity [Abstract]  
Schedule of Changes in Stockholders’ Equity

The following tables present changes in stockholders’ equity for the nine-month periods ended September 30, 2021 and 2020 (in thousands, except share data):

 

 

 

 

 

 

 

Additional

 

 

Accumulated Other

 

 

 

 

 

Total

 

 

Common

 

 

Paid-In

 

 

Comprehensive

 

 

Accumulated

 

 

Stockholders’

 

 

Shares

 

 

Amount

 

 

Capital

 

 

Income (Loss)

 

 

Deficit

 

 

Equity

 

Balance at December 31, 2020

 

66,234,056

 

 

$

7

 

 

$

962,173

 

 

$

1

 

 

$

(435,109

)

 

$

527,072

 

Issuance of common stock through
   at-the-market offerings, net of
   issuance costs of $
52

 

641,709

 

 

 

-

 

 

 

45,255

 

 

 

-

 

 

 

-

 

 

 

45,255

 

Exercise of stock options

 

1,014,569

 

 

 

-

 

 

 

13,340

 

 

 

-

 

 

 

-

 

 

 

13,340

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

6,424

 

 

 

-

 

 

 

-

 

 

 

6,424

 

Other comprehensive loss

 

-

 

 

 

-

 

 

 

-

 

 

 

(13

)

 

 

-

 

 

 

(13

)

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(46,205

)

 

 

(46,205

)

Balance at March 31, 2021

 

67,890,334

 

 

 

7

 

 

 

1,027,192

 

 

 

(12

)

 

 

(481,314

)

 

 

545,873

 

Exercise of stock options

 

394,801

 

 

 

-

 

 

 

6,163

 

 

 

-

 

 

 

-

 

 

 

6,163

 

Vesting of restricted stock units

 

26,235

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

Issuance of shares under employee
   stock purchase plan

 

20,410

 

 

 

-

 

 

 

970

 

 

 

-

 

 

 

-

 

 

 

970

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

10,614

 

 

 

-

 

 

 

-

 

 

 

10,614

 

Other comprehensive loss

 

-

 

 

 

-

 

 

 

-

 

 

 

(1

)

 

 

-

 

 

 

(1

)

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(68,806

)

 

 

(68,806

)

Balance at June 30, 2021

 

68,331,780

 

 

 

7

 

 

 

1,044,939

 

 

 

(13

)

 

 

(550,120

)

 

 

494,813

 

Issuance of common stock through
   follow-on offering, net of
   issuance costs of $
284

 

4,758,620

 

 

 

-

 

 

 

648,315

 

 

 

-

 

 

 

-

 

 

 

648,315

 

Exercise of stock options

 

1,227,067

 

 

 

-

 

 

 

20,365

 

 

 

-

 

 

 

-

 

 

 

20,365

 

Vesting of restricted stock units

 

24,711

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

15,410

 

 

 

-

 

 

 

-

 

 

 

15,410

 

Other comprehensive loss

 

-

 

 

 

-

 

 

 

-

 

 

 

(161

)

 

 

-

 

 

 

(161

)

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(71,644

)

 

 

(71,644

)

Balance at September 30, 2021

 

74,342,178

 

 

$

7

 

 

$

1,729,029

 

 

$

(174

)

 

$

(621,764

)

 

$

1,107,098

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Additional

 

 

Accumulated Other

 

 

 

 

 

Total

 

 

Common

 

 

Paid-In

 

 

Comprehensive

 

 

Accumulated

 

 

Stockholders’

 

 

Shares

 

 

Amount

 

 

Capital

 

 

Income

 

 

Deficit

 

 

Equity

 

Balance at December 31, 2019

 

50,198,044

 

 

$

5

 

 

$

570,493

 

 

$

261

 

 

$

(300,878

)

 

$

269,881

 

Issuance of common stock through
   at-the-market offerings, net of
   issuance costs of $
48

 

351,252

 

 

 

-

 

 

 

5,079

 

 

 

-

 

 

 

-

 

 

 

5,079

 

Exercise of stock options

 

53,579

 

 

 

-

 

 

 

336

 

 

 

-

 

 

 

-

 

 

 

336

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

4,157

 

 

 

-

 

 

 

-

 

 

 

4,157

 

Other comprehensive income

 

-

 

 

 

-

 

 

 

-

 

 

 

112

 

 

 

-

 

 

 

112

 

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(31,806

)

 

 

(31,806

)

Balance at March 31, 2020

 

50,602,875

 

 

 

5

 

 

 

580,065

 

 

 

373

 

 

 

(332,684

)

 

 

247,759

 

Issuance of common stock through
   follow-on offering, net of
   issuance costs of $
369

 

6,301,370

 

 

 

1

 

 

 

107,731

 

 

 

-

 

 

 

-

 

 

 

107,732

 

Issuance of common stock in
   private placement with Regeneron

 

925,218

 

 

 

-

 

 

 

12,580

 

 

 

-

 

 

 

-

 

 

 

12,580

 

Issuance of common stock through
   at-the-market offerings, net of
   issuance costs of $
23

 

755,848

 

 

 

-

 

 

 

9,643

 

 

 

-

 

 

 

-

 

 

 

9,643

 

Exercise of stock options

 

83,631

 

 

 

-

 

 

 

1,035

 

 

 

-

 

 

 

-

 

 

 

1,035

 

Issuance of shares under employee
   stock purchase plan

 

55,296

 

 

 

-

 

 

 

685

 

 

 

-

 

 

 

-

 

 

 

685

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

4,764

 

 

 

-

 

 

 

-

 

 

 

4,764

 

Other comprehensive loss

 

-

 

 

 

-

 

 

 

-

 

 

 

(218

)

 

 

-

 

 

 

(218

)

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(32,393

)

 

 

(32,393

)

Balance at June 30, 2020

 

58,724,238

 

 

 

6

 

 

 

716,503

 

 

 

155

 

 

 

(365,077

)

 

 

351,587

 

Exercise of stock options

 

67,974

 

 

 

-

 

 

 

597

 

 

 

-

 

 

 

-

 

 

 

597

 

Equity-based compensation

 

-

 

 

 

-

 

 

 

5,400

 

 

 

-

 

 

 

-

 

 

 

5,400

 

Other comprehensive loss

 

-

 

 

 

-

 

 

 

-

 

 

 

(124

)

 

 

-

 

 

 

(124

)

Net loss

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(27,840

)

 

 

(27,840

)

Balance at September 30, 2020

 

58,792,212

 

 

$

6

 

 

$

722,500

 

 

$

31

 

 

$

(392,917

)

 

$

329,620