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Exhibit 99.1

Condensed Consolidated Balance Sheets (Unaudited)

(in CHF thousands)

As of September 30, 

As of December 31, 

Balance Sheets

    

Notes

    

2022

    

2021

ASSETS

 

  

 

  

 

  

Non-current assets

 

  

 

  

 

  

Property, plant and equipment

 

5

 

4,687

 

5,116

Right-of-use assets

 

6

 

2,491

 

2,914

Intangible asset

 

9

 

50,416

 

50,416

Long-term financial assets

 

6

 

361

 

363

Total non-current assets

 

57,955

 

58,809

Current assets

 

 

Prepaid expenses

 

10

 

2,888

 

3,015

Accrued income

 

3

 

50

 

975

Other current receivables

 

3

 

4,161

 

428

Short-term financial assets

 

11

 

96,000

 

116,000

Cash and cash equivalents

 

11

 

44,503

 

82,216

Total current assets

 

147,602

 

202,634

Total assets

 

205,557

 

261,443

SHAREHOLDERS’ EQUITY AND LIABILITIES

 

 

Shareholders’ equity

 

 

Share capital

 

 

1,797

 

1,794

Share premium

 

 

431,303

 

431,251

Treasury shares

 

12

 

(124)

 

(124)

Currency translation differences

72

Accumulated losses

 

(242,994)

 

(200,942)

Total shareholders’ equity

 

190,054

 

231,979

Non-current liabilities

 

 

Long-term lease liabilities

 

6

 

1,903

 

2,340

Net employee defined benefit liabilities

 

7

 

 

7,098

Total non-current liabilities

 

1,903

 

9,438

Current liabilities

 

 

Trade and other payables

 

 

1,519

 

2,003

Accrued expenses

 

8

 

10,976

 

16,736

Deferred income

 

3

 

524

 

717

Short-term lease liabilities

 

6

 

581

 

570

Total current liabilities

 

13,600

 

20,026

Total liabilities

 

15,503

 

29,464

Total shareholders’ equity and liabilities

 

205,557

 

261,443

The accompanying notes are an integral part of these Interim Condensed Consolidated Financial Statements (Unaudited).

Condensed Consolidated Statements of Income/(Loss) (Unaudited)

(in CHF thousands except for per share data)

For the Three Months

For the Nine Months

Ended September 30, 

Ended September 30, 

Notes

2022

2021

2022

2021

Revenue

    

  

    

  

    

  

    

  

    

  

Contract revenue

 

3

 

3,934

 

 

3,934

 

Total revenue

 

3,934

 

 

3,934

 

 

 

 

 

Operating expenses

 

 

 

 

Research & development expenses

 

 

(14,385)

 

(15,118)

 

(45,200)

 

(42,158)

General & administrative expenses

 

 

(3,274)

 

(5,420)

 

(11,828)

 

(14,993)

Other operating income/(expense)

 

3

 

262

 

255

 

944

 

928

Total operating expenses

 

(17,397)

 

(20,283)

 

(56,084)

 

(56,223)

Operating loss

 

(13,463)

 

(20,283)

 

(52,150)

 

(56,223)

Financial income

 

 

11

 

4,424

 

11

 

4,424

Financial expense

 

 

(77)

 

(181)

 

(356)

 

(408)

Exchange differences

 

 

17

 

122

 

502

 

487

Finance result, net

13

 

(49)

 

4,365

 

157

 

4,503

Loss before tax

 

(13,512)

 

(15,918)

 

(51,993)

 

(51,720)

Income tax expense

 

 

(4)

 

 

(11)

 

Loss for the period

 

(13,516)

 

(15,918)

 

(52,004)

 

(51,720)

Loss per share:

4

 

 

 

 

Basic and diluted loss per share for the period attributable to equity holders

 

 

(0.16)

 

(0.22)

 

(0.62)

 

(0.71)

Condensed Consolidated Statements of

For the Three Months

For the Nine Months

Comprehensive Income/(Loss) (Unaudited)

ended September 30, 

ended September 30, 

(in CHF thousands)

    

Notes

    

2022

    

2021

    

2022

    

2021

Loss for the period

 

(13,516)

 

(15,918)

 

(52,004)

 

(51,720)

Items that will be reclassified to income or loss in subsequent periods (net of tax):

 

 

 

 

Currency translation differences

 

23

 

 

72

 

Items that will not to be reclassified to income or loss in subsequent periods (net of tax):

 

 

 

 

Remeasurement gains on defined-benefit plans (net of tax)

 

7

 

178

 

 

7,559

 

Total comprehensive loss, net of tax

 

(13,315)

 

(15,918)

 

(44,373)

 

(51,720)

The accompanying notes are an integral part of these Interim Condensed Consolidated Financial Statements (Unaudited).

2

Condensed Consolidated Statements of Changes in Equity (Unaudited)

(in CHF thousands)

    

    

    

    

    

    

Currency

    

Share

Share

Treasury

Accumulated

Translation

    

Notes

    

capital

    

premium

    

shares

    

losses

    

Differences

    

Total

Balance as of January 1, 2021

1,538

346,890

(100)

(132,850)

215,478

Net loss for the period

(51,720)

(51,720)

Other comprehensive income/(loss)

 

 

 

 

 

 

 

Total comprehensive loss

 

 

 

 

 

(51,720)

 

 

(51,720)

 

 

 

Share-based payments

 

 

 

 

3,081

 

 

3,081

Proceeds from sale of treasury shares in public offerings, net of underwriting fees and transaction costs

 

12

 

12,097

 

24

 

 

 

12,121

Issuance of shares, net of transaction costs:

 

 

  

 

  

 

  

 

  

 

  

 

  

held as treasury shares

12

48

(48)

restricted share awards

 

 

1

 

169

 

 

(176)

 

 

(6)

exercise of options

 

 

2

 

265

 

 

 

 

267

Balance as of September 30, 2021

 

 

1,589

 

359,421

 

(124)

 

(181,665)

 

 

179,221

    

    

    

    

    

    

Currency

    

Share

Share

Treasury

Accumulated

Translation

    

Notes

    

capital

    

premium

    

shares

    

losses

    

Differences

    

Total

Balance as of January 1, 2022

 

1,794

 

431,251

 

(124)

 

(200,942)

 

 

231,979

Net loss for the period

 

 

 

 

(52,004)

 

 

(52,004)

Other comprehensive income/(loss)

 

7

 

 

 

 

7,559

 

72

 

7,631

Total comprehensive loss

 

 

 

 

(44,445)

 

72

 

(44,373)

 

 

Share-based payments

 

 

 

 

2,441

 

 

2,441

Issuance of shares, net of transaction costs:

 

 

 

  

 

 

 

restricted share awards

 

 

48

 

 

(48)

 

 

exercise of options

 

3

 

4

 

 

 

 

7

Balance as of September 30, 2022

 

1,797

 

431,303

 

(124)

 

(242,994)

 

72

 

190,054

The accompanying notes are an integral part of these Interim Condensed Consolidated Financial Statements (Unaudited).

3

Condensed Consolidated Statements of Cash Flows (Unaudited)

(in CHF thousands)

For the Nine Months

Ended September 30, 

Notes

2022

2021

Operating activities

    

  

    

  

    

  

    

Loss for the period

 

(52,004)

 

(51,720)

Adjustments to reconcile net loss for the period to net cash flows:

 

 

Depreciation of property, plant and equipment

 

5

 

1,331

 

1,411

 

Depreciation of right-of-use assets

 

6

 

423

 

367

 

Finance (income), net

 

13

 

(743)

 

(4,954)

 

Share-based compensation expense

 

 

2,441

 

3,081

 

Change in net employee defined benefit liability

 

 

461

 

465

 

Interest expense

 

13

 

349

 

402

 

Changes in working capital:

 

  

 

  

(Increase)/decrease in prepaid expenses

 

10

 

(165)

 

1,900

 

Decrease in accrued income

 

3

 

940

 

1,447

 

(Increase) in other current receivables

 

 

(3,802)

 

(11)

 

(Decrease) / increase in accrued expenses

 

8

 

(4,440)

 

2,128

 

(Decrease) in deferred income

 

3

 

(207)

 

(141)

 

(Decrease) in trade and other payables

 

 

(372)

 

(1,897)

 

Cash used in operating activities

 

(55,788)

 

(47,522)

Interest received

 

 

11

 

 

Interest paid

 

 

(376)

 

(334)

 

Finance costs

 

 

(8)

 

(5)

 

Net cash flows used in operating activities

 

(56,161)

 

(47,861)

 

  

 

  

Investing activities

 

  

 

  

Short-term financial assets, net

 

11

 

20,000

 

(30,000)

 

Purchases of property, plant and equipment

 

5

 

(1,198)

 

(1,913)

 

Rental deposits

 

6

 

2

 

(29)

 

Net cash flows provided by/(used in) investing activities

 

18,804

 

(31,942)

 

  

 

  

Financing activities

 

  

 

  

Principal payments of lease obligations

 

6

 

(426)

 

(369)

 

Proceeds from sale of treasury shares in public offerings, net of underwriting fees and transaction costs

12

12,121

Transaction costs associated with issuance of shares in relation to asset acquisition previously recorded in accrued expenses

(776)

Proceeds from issuance of common shares

7

261

Net cash flows (used in)/provided by financing activities

 

(1,195)

 

12,013

 

  

 

  

Net decrease in cash and cash equivalents

 

(38,552)

 

(67,790)

Cash and cash equivalents at January 1

 

82,216

 

160,893

Exchange gain on cash and cash equivalents

 

839

 

481

Cash and cash equivalents at September 30

 

44,503

 

93,584

Net decrease in cash and cash equivalents

 

(38,552)

 

(67,790)

Supplemental non-cash activity

 

  

 

  

Capital expenditures in Trade and other payables or Accrued expenses

 

5

 

7

 

137

 

The accompanying notes are an integral part of these Interim Condensed Consolidated Financial Statements (Unaudited).

4

Notes to the Interim Condensed Consolidated Financial Statements (Unaudited)
(in CHF thousands, except share and per share amounts)

1.Corporate information

AC Immune SA was founded in 2003. The Company controls a fully-owned subsidiary, AC Immune USA, Inc. (“AC Immune USA” or “Subsidiary” and, together with AC Immune SA, “AC Immune,” “ACIU,” “Company,” “we,” “our,” “ours,” “us”), which was organized under the laws of Delaware, USA in June 2021. The Company and its Subsidiary form the Group (See “Note 2. Basis of preparation and changes to the Company’s accounting policies”).

AC Immune SA is a clinical-stage biopharmaceutical company leveraging our two proprietary technology platforms to discover, design and develop novel proprietary medicines and diagnostics for prevention and treatment of neurodegenerative diseases (NDD) associated with protein misfolding. Misfolded proteins are generally recognized as the leading cause of NDD, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), with common mechanisms and drug targets, such as amyloid beta (Abeta), Tau, alpha-synuclein (a-syn) and TDP-43. Our corporate strategy is founded upon a three-pillar approach that targets (i) AD, (ii) focused non-AD NDD including Parkinson’s disease, ALS and NeuroOrphan indications and (iii) diagnostics. We use our two unique proprietary platform technologies, SupraAntigen (conformation-specific biologics) and Morphomer (conformation-specific small molecules), to discover, design and develop novel medicines and diagnostics to target misfolded proteins.

The Interim Condensed Consolidated Financial Statements of AC Immune SA as of and for the three and nine months ended September 30, 2022 were authorized for issuance by the Company’s Audit and Finance Committee on October 27, 2022.

2.Basis of preparation and changes to the Company’s accounting policies

Statement of compliance

These Interim Condensed Consolidated Financial Statements as of September 30, 2022 and for the three and nine months ended September 30, 2022 and 2021, have been prepared in accordance with International Accounting Standard 34 (IAS 34), Interim Financial Reporting, as issued by the International Accounting Standards Board (IASB), and such financial information should be read in conjunction with the audited consolidated financial statements in AC Immune’s Annual Report on Form 20-F for the year ended December 31, 2021.

Basis of measurement

These Interim Condensed Consolidated Financial Statements have been prepared under the historical cost convention.

Functional and reporting currency

These Interim Condensed Consolidated Financial Statements and accompanying notes are presented in Swiss Francs (CHF), which is AC Immune SA’s functional currency and the Group’s reporting currency. The Company’s subsidiary has a functional currency of the US Dollar (USD). The following exchange rates have been used for the translation of the financial statements of AC Immune USA:

    

For the Three Months

    

For the Nine Months

Ended September 30, 

Ended September 30, 

2022

    

2021

2022

    

2021

CHF/USD

 

  

 

  

 

  

 

  

Closing rate, USD 1

 

0.985

 

0.943

 

0.985

 

0.943

Weighted average exchange rate, USD 1

 

0.976

 

0.927

 

0.962

 

0.920

5

Critical judgments and accounting estimates

The preparation of the Company’s Interim Condensed Consolidated Financial Statements in conformity with IAS 34 requires management to make judgments, estimates and assumptions that affect the amounts reported in the Interim Condensed Consolidated Financial Statements and accompanying notes, and the related application of accounting policies as it relates to the reported amounts of assets, liabilities, income and expenses.

The areas where AC Immune has had to make judgments, estimates and assumptions relate to (i) revenue recognition on Licensing and Collaboration Agreements, (ii) clinical development accruals, (iii) net employee defined benefit liability, (iv) income taxes, (v) share-based compensation, (vi) right-of-use assets and lease liabilities and (vii) our IPR&D asset. Actual results may differ from these estimates. Estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognized in the period in which the estimates are revised and in any future periods affected.

Fair value of financial assets and liabilities

The Company’s financial assets and liabilities are composed of receivables, short-term and long-term financial assets, cash and cash equivalents, trade and other payables, accrued expenses and lease liabilities. The fair value of these financial instruments approximates their respective carrying values due to the short-term maturity of these instruments, and are held at their amortized cost in accordance with IFRS 9, unless otherwise explicitly noted.

Accounting policies, new standards, interpretations and amendments adopted by the Company

The accounting policies adopted in the preparation of the Interim Condensed Consolidated Financial Statements are consistent with those followed in the preparation of the Company’s annual consolidated financial statements for the year ended December 31, 2021.

The Company has not adopted any other standard, interpretation or amendment that has been issued but is not yet effective. Such standards are not currently expected to have a material impact on the entity in the current or future reporting periods, and on foreseeable future transactions.

Going concern

The Company believes that it will be able to meet all of its obligations as they fall due for at least 12 months from September 30, 2022, after considering the Company’s cash position of CHF 44.5 million and short-term financial assets of CHF 96.0 million as of September 30, 2022. Hence, the unaudited Interim Condensed Consolidated Financial Statements have been prepared on a going-concern basis.

To date, the Company has financed its cash requirements primarily from its public offerings, share issuances, contract revenues from license and collaboration agreements and grants. The Company is a clinical-stage company and is exposed to all the risks inherent to establishing a business. Inherent to the Company’s business are various risks and uncertainties, including the substantial uncertainty as to whether current projects will succeed. The Company’s success may depend in part upon its ability to (i) establish and maintain a strong patent position and protection, (ii) enter into collaborations with partners in the pharmaceutical and biopharmaceutical industries, (iii) successfully move its product candidates through clinical development, (iv) attract and retain key personnel and (v) acquire capital to support its operations.

In addition to the foregoing, based on the Company’s current assessment, the Company does not expect any material impact on its long-term development timeline, its liquidity or ability to remain a going concern due to the worldwide spread of the Covid-19 virus. The Company continues to assess the effect on its operations by carefully monitoring the spread of Covid-19 and taking appropriate steps intended to offset any negative impacts from the Covid-19 virus.

6

3.Contract revenues and other operating income

For the three and nine months ended September 30, 2022, AC Immune generated CHF 3.9 million in contract revenues compared with no contract revenues in the prior comparable periods, respectively.

For the Three Months

Ended September 30,

in CHF thousands

    

2022

    

2021

Life Molecular Imaging

 

3,934

 

Total contract revenue

 

3,934

 

For the Nine Months

Ended September 30,

in CHF thousands

    

2022

    

2021

Life Molecular Imaging

 

3,934

 

Total contract revenue

 

3,934

 

The following table presents changes in the Company’s contract assets and liabilities during the nine months ended September 30, 2022 and 2021:

    

Balance at

    

    

    

the

Balance at

beginning

the end of

of the

the

reporting

reporting

in CHF thousands

period

Additions

Deductions

period

Nine months ended September 30, 2022:

 

  

 

  

 

  

 

  

Accrued income

 

975

 

1,079

 

(2,004)

 

50

Deferred income

 

717

 

733

 

(926)

 

524

Nine months ended September 30, 2021:

 

  

 

  

 

  

 

  

Accrued income

 

1,591

 

781

 

(2,249)

 

123

Deferred income

 

306

 

781

 

(933)

 

154

3.1Licensing and collaboration agreements

For a discussion of our licensing and collaboration agreements for the fiscal year ended December 31, 2021, please refer to Note 13.1 “Licensing and Collaboration agreements” of our Annual Report on Form 20-F for the year ended December 31, 2021 filed on March 22, 2022.

During the three and nine months ended September 30, 2022 and 2021, the Company recognized the following contract revenues as a result of performance obligations satisfied in previous periods:

For the Three Months

Ended September 30,

in CHF thousands

    

2022

    

2021

Revenue recognized in the period from:

 

    

 

  

Amounts included in the contract liability at the beginning of the period

 

 

Performance obligations satisfied in previous periods

 

3,934

 

For the Nine Months

Ended September 30,

in CHF thousands

    

2022

    

2021

Revenue recognized in the period from:

 

  

 

  

Amounts included in the contract liability at the beginning of the period

 

 

Performance obligations satisfied in previous periods

 

3,934

 

7

As it relates to contract revenue recognition, in September 2022, the Company earned a milestone linked to the progression of the Tau PET Tracer PI-2620 partnered with Life Molecular Imaging (LMI) into late-stage development in Alzheimer’s disease. The Company recorded EUR 4 (CHF 3.9) million in contract revenue for the three and nine months ended September 30, 2022 as a result of achieving this milestone. The Company recorded this EUR 4 (CHF 3.9) million milestone within other current receivables on its condensed consolidated balance sheets as of September 30, 2022.

3.2Grant income

Grants from the Michael J. Fox Foundation

For a discussion of our Grants from the Michael J. Fox Foundation (MJFF) for the fiscal year ended December 31, 2021, please refer to Note 13.2 “Grant Income” of our Annual Report on Form 20-F for the year ended December 31, 2021 filed on March 22, 2022.

In August 2022, the Company received follow-om grant funding as part of its joint arrangement with Skåne University Hospital (Skåne) in Sweden totaling USD 0.5 (CHF 0.5) million for the continued development of its alpha-synuclein PET imaging diagnostic agent. As part of this grant, AC Immune received USD 0.4 (CHF 0.4) million directly from the MJFF. Skåne will receive USD 0.1 (CHF 0.1) million of the total grant directly from the MJFF duration of the grant period.

For the three months ended September 30, 2022 and 2021, the Company has recognized CHF 0.2 million in grant income, respectively. For the nine months ended September 30, 2022 and 2021, the Company has recognized CHF 0.8 million in grant income, respectively. As of September 30, 2022, the Company has recorded CHF 0.5 million in deferred income, respectively.

Grant from the Target ALS Foundation

For a discussion of our Grants from the Target ALS Foundation (Target ALS) for the fiscal year ended December 31, 2021, please refer to Note 13.2 “Grant Income” of our Annual Report on Form 20-F for the year ended December 31, 2021 filed on March 22, 2022.

For the three and nine months ended September 30, 2022 and 2021, the Company recognized less than CHF 0.1 million and CHF 0.1 million, respectively. As of September 30, 2022, the Company has recorded less than CHF 0.1 million in deferred income.

4.Loss per share

8

    

For the Three Months

Ended September 30, 

in CHF thousands except for share and per share data

    

2022

    

2021

Loss per share (EPS)

 

  

 

  

Numerator

 

  

 

  

Net loss attributable to equity holders of the Company

 

(13,516)

 

(15,918)

Denominator

 

  

 

  

Weighted-average number of shares outstanding used to compute EPS basic and diluted attributable to equity holders

 

83,590,948

 

72,887,967

Basic and diluted loss per share for the period attributable to equity holders

 

(0.16)

 

(0.22)

For the Nine Months

Ended September 30, 

in CHF thousands except for share and per share data

    

2022

2021

Loss per share (EPS)

  

    

  

Numerator

  

 

  

Net loss attributable to equity holders of the Company

(52,004)

 

(51,720)

Denominator

 

Weighted-average number of shares outstanding used to compute EPS basic and diluted attributable to equity holders

83,537,655

 

72,638,698

Basic and diluted loss per share for the period attributable to equity holders

(0.62)

 

(0.71)

Potentially dilutive securities that were not included in the diluted per share calculations because they would be anti-dilutive were as follows:

    

For the Three Months

Ended September 30, 

    

2022

    

2021

Share options issued and outstanding

 

97,875

 

1,267,924

Restricted share awards subject to future vesting

 

240,923

 

1,244

For the Nine Months

Ended September 30, 

2022

2021

Share options issued and outstanding

    

148,617

    

1,172,439

Restricted share awards subject to future vesting

 

85,829

 

8,106

9

5.Property, plant and equipment

The following table shows the movement in the net book values of property, plant and equipment for the nine months ended September 30, 2022:

    

As of September 30, 2022

    

IT

    

Lab

    

Leasehold

    

Assets Under

    

in CHF thousands

Furniture

Equipment

Equipment

Improvements

Construction

Total

Acquisition Cost

 

  

 

  

 

  

 

  

 

  

 

  

Balance at December 31, 2021

 

263

 

1,756

 

9,142

 

810

 

695

 

12,666

Additions

 

19

 

149

 

559

 

165

 

10

 

902

Transfers

 

 

4

 

47

 

646

 

(697)

 

Balance at September 30, 2022

 

282

 

1,909

 

9,748

 

1,621

 

8

 

13,568

Accumulated depreciation

 

 

 

 

 

 

Balance at December 31, 2021

 

(106)

 

(1,316)

 

(5,739)

 

(389)

 

 

(7,550)

Depreciation expense

 

(39)

 

(215)

 

(966)

 

(111)

 

 

(1,331)

Balance at September 30, 2022

 

(145)

 

(1,531)

 

(6,705)

 

(500)

 

 

(8,881)

Carrying Amount

 

 

  

 

  

 

  

 

  

 

  

December 31, 2021

 

157

 

440

 

3,403

 

421

 

695

 

5,116

September 30, 2022

 

137

 

378

 

3,043

 

1,121

 

8

 

4,687

AC Immune continues to enhance its laboratory equipment to support its R&D functions and IT equipment. This effort has continued since the year ended December 31, 2021, with CHF 0.8 million invested in lab equipment, including the expansion of our leased lab space, and IT equipment, representing an increase of 7.0% from the beginning of the year in these categories.

6.Right-of-use assets, long-term financial assets and lease liabilities

AC Immune recognized no additions for its right-of-use of leased assets for the nine months ended September 30, 2022.

Regarding lease liabilities, the amortization depends on the rate implicit in the contract or the incremental borrowing rate for the respective lease component. The weighted averages of the incremental borrowing rates are 2.5% for buildings, 5.3% for office equipment and 2.6% for IT equipment, respectively.

The following table shows the movements in the net book values of right-of-use of leased assets for the nine months ended September 30, 2022:

    

    

Office

    

IT

    

in CHF thousands

Buildings

Equipment

Equipment

Total

Balance as of December 31, 2021

 

2,776

 

98

 

40

 

2,914

Depreciation

 

(395)

 

(17)

 

(11)

 

(423)

Balance as of September 30, 2022

 

2,381

 

81

 

29

 

2,491

There are no variable lease payments that are not included in the measurement of lease obligations. All extension options have been included in the measurement of lease obligations.

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For the three and nine months ended September 30, 2022, and 2021, the impact on the Company’s condensed consolidated statements of income/(loss) and the condensed consolidated statements of cash flows is as follows:

For the Three Months

Ended September 30, 

in CHF thousands

    

2022

    

2021

Statements of income/(loss)

 

  

 

  

Depreciation of right-of-use assets

 

142

 

141

Interest expense on lease liabilities

 

17

 

17

Expense for short-term leases and leases of low value

 

212

 

231

Total

 

371

 

389

Statements of cash flows

 

 

  

Total cash outflow for leases

 

371

 

389

For the Nine Months

Ended September 30, 

in CHF thousands

    

2022

    

2021

Statements of income/(loss)

 

  

 

  

Depreciation of right-of-use assets

 

423

 

367

Interest expense on lease liabilities

 

53

 

47

Expense for short-term leases and leases of low value

 

559

 

587

Total

 

1,035

 

1,001

Statements of cash flows

 

 

  

Total cash outflow for leases

 

1,037

 

1,001

The following table presents the contractual undiscounted cash flows for lease obligations as of September 30, 2022:

As of

in CHF thousands

    

September 30, 2022

Less than one year

 

638

1-3 years

 

1,238

3-5 years

 

748

Total

 

2,624

The Company also has deposits in escrow accounts totaling CHF 0.4 million for leases of the Company’s premises as of both September 30, 2022 and December 31, 2021, respectively. These deposits are presented in Long-term financial assets on the Company’s condensed consolidated balance sheets.

7.Net employee defined benefit liabilities

The Company used its independent actuaries to update the calculation of the defined benefit obligation and plan assets in Q2 2022. For the three and nine months ended September 30, 2022, the Company recognized a remeasurement gain of CHF 0.2 million and CHF 7.6 million on the Company’s condensed consolidated statements of comprehensive income/(loss) related to its net employee defined benefit liability, respectively. The primary component of the remeasurement gain as for the nine months period ended September 30, 2022 relates to the increase in the discount rate by 195 basis points to 2.25% from 0.3% as of December 31, 2021.

The resulting impact as a result of the asset ceiling test is to record nil for the net employee defined benefit liability on the Company’s condensed consolidated balance sheets as of September 30, 2022 compared to CHF 7.1 million as of December 31, 2021.

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8.Accrued expenses

    

As of

    

September 30, 

    

December 31, 

in CHF thousands

2022

2021

Accrued Expenses

 

10,976

 

16,736

Total

 

10,976

 

16,736

The Company paid CHF 3.7 million in the period for a previous accrual associated with our cost sharing arrangement with Janssen and CHF 2.3 million related to performance-related remuneration for the nine months ended September 30, 2022.

9.Intangible assets

AC Immune’s acquired IPR&D asset is a clinically-validated active vaccine candidate for the treatment of Parkinson’s disease. The asset is not yet ready for use until the asset obtains market approval and is therefore not currently being amortized. The carrying amount and net book value are detailed below:

    

As of September 30, 2022

As of December 31, 2021

    

Gross

    

    

    

Gross

    

    

Carrying

Accumulated

Net Book

Carrying

Accumulated

Net Book

In CHF thousands

Amount

Amortization

Value

Amount

Amortization

Value

Acquired IPR&D Asset

50,416

 

 

50,416

 

50,416

 

 

50,416

Total Intangible Assets

50,416

 

 

50,416

 

50,416

 

 

50,416

In accordance with IAS 36 Impairment of Assets, the IPR&D asset is reviewed at least annually for impairment by assessing the fair value less costs to sell (recoverable amount) and comparing this to the carrying value of the asset. The valuation is considered to be Level 3 in the fair value hierarchy in accordance with IFRS 13 Fair Value Measurement due to unobservable inputs used in the valuation. The Company has determined the IPR&D asset not to be impaired as of September 30, 2022.

10.Prepaid expenses

Prepaid expenses include prepaid R&D costs, administrative costs and employee social obligations totaling CHF 2.9 million and CHF 3.0 million as of September 30, 2022 and December 31, 2021, respectively.

11.Cash and cash equivalents and financial assets

The following table summarizes AC Immune’s cash and cash equivalents and short-term financial assets as of September 30, 2022 and December 31, 2021:

    

As of

in CHF thousands

September 30, 2022

    

December 31, 2021

Cash and cash equivalents

 

44,503

 

82,216

Total

 

44,503

 

82,216

    

As of

in CHF thousands

September 30, 2022

    

December 31, 2021

Short-term financial assets due in one year or less

 

96,000

 

116,000

Total

 

96,000

 

116,000

For the nine months ended September 30, 2022, the Company sold a net CHF 20.0 million in short-term financial assets compared with purchasing a net CHF 30.0 million for the prior period.

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12.Treasury shares

For a discussion of our at the market offering program with Jefferies LLC for the fiscal year ended December 31, 2021, please refer to Note 11 “Share capital” of our Annual Report on Form 20-F for the year ended December 31, 2021 filed on March 22, 2022.

As of September 30, 2022, the Company has 6,221,617 treasury shares remaining.

13.Finance result, net

For the three months ended September 30, 2022 and 2021, AC Immune recorded less than CHF 0.1 million in net financial losses and CHF 4.4 million in net financial gains, respectively. The Company recorded CHF 4.4 million in finance income associated with the change in fair value of derivative financial assets in the prior period which did not repeat in the current period.

For the nine months ended September 30, 2022 and 2021, the Company recorded CHF 0.2 million and CHF 4.5 million in net financial gains, respectively. The Company recorded CHF 4.4 million in finance income associated with the change in fair value of derivative financial assets in the prior period which did not repeat in the current period.

14.Subsequent events

Management has evaluated subsequent events after the balance sheet date, through the issuance of these Interim Condensed Consolidated Financial Statements, for appropriate accounting and disclosures. The Company has determined that there were no other such events that warrant disclosure or recognition in these Interim Condensed Consolidated Financial Statements.

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