Segment and Geographic Information - Narratives (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2023 USD ($) segment	Mar. 31, 2022 USD ($)
Segment information
Number of operating segments | segment	1
Total revenues	$ 447,801	$ 306,626
United States
Segment information
Total revenues	165,025	99,425
Collaboration revenue
Segment information
Total revenues	37,510	45,053
Collaboration revenue | Rest Of World
Segment information
Total revenues		13,516
Product revenue, net
Segment information
Total revenues	410,291	261,573
Product revenue, net | Rest Of World
Segment information
Total revenues		2,950
BRUKINSA® | Collaboration revenue | United States
Segment information
Total revenues	26,257	31,537
BRUKINSA® | Collaboration revenue | Rest Of World
Segment information
Total revenues	11,253
BRUKINSA® | Product revenue, net
Segment information
Total revenues	211,382	104,325
BRUKINSA® | Product revenue, net | United States
Segment information
Total revenues	138,768	$ 67,888
BRUKINSA® | Product revenue, net | Rest Of World
Segment information
Total revenues	$ 24,615