Collaborative and Licensing Arrangements - Amounts and Classification of Payments (Income/(Expense) (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Research and Development Arrangement, Contract to Perform for Others
Total	$ (11,583)	$ (11,711)
Amgen, Inc | Collaborative Arrangement
Research and Development Arrangement, Contract to Perform for Others
Collaborative arrangement, inventory purchases	19,131	7,599
Accounts payable current	22,950		$ 54,064
Cost of sales - product
Research and Development Arrangement, Contract to Perform for Others
Total	(2,827)	1,029
Research and development
Research and Development Arrangement, Contract to Perform for Others
Total	3,080	241
Selling, general and administrative
Research and Development Arrangement, Contract to Perform for Others
Total	$ (11,836)	$ (12,981)