Commitments and Contingencies - Milestones (Details) $ in Millions	Dec. 31, 2024 USD ($)
Cas-9 License Agreement
Commitments and Contingencies [Line Items]
License agreement, sales milestone payments payable	$ 54.0
License agreement, reduction in clinical and regulatory milestone payments payable	4.1
License agreement, reduction in sales milestone payments payable	36.0
Cpf1 License Agreement
Commitments and Contingencies [Line Items]
License agreement, sales milestone payments payable	54.0
License agreement, reduction in clinical and regulatory milestone payments payable	5.5
License agreement, reduction in sales milestone payments payable	36.0
Cas9-II License Agreement
Commitments and Contingencies [Line Items]
License agreement, sales milestone payments payable	13.5
License agreement, reduction in clinical and regulatory milestone payments payable	1.1
License agreement, reduction in sales milestone payments payable	9.0
Maximum | Cas-9 License Agreement
Commitments and Contingencies [Line Items]
License agreement, clinical and regulatory milestone payments payable	14.8
Maximum | Cpf1 License Agreement
Commitments and Contingencies [Line Items]
License agreement, clinical and regulatory milestone payments payable	20.0
Maximum | Cas9-II License Agreement
Commitments and Contingencies [Line Items]
License agreement, clinical and regulatory milestone payments payable	$ 3.7