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Accrued Expenses (Details) - USD ($)
$ in Thousands
Mar. 31, 2022
Dec. 31, 2021
Accrued Expenses    
Employee related expenses $ 5,581 $ 10,159
External research and development expenses 5,392 5,614
Intellectual property and patent related fees 2,967 1,408
Professional service expenses 1,037 2,345
Other expenses 810 666
Total accrued expenses $ 15,787 $ 20,192