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Common Stock - Stock Incentive Plan (Details)
1 Months Ended 12 Months Ended
Jan. 31, 2021
shares
Nov. 30, 2020
shares
Dec. 31, 2020
item
$ / shares
shares
Dec. 31, 2019
shares
Jul. 31, 2015
shares
Sep. 30, 2013
shares
Stock-based compensation disclosures            
Shares reserved for future awards     12,030,284 10,433,255    
Stock options            
Stock-based compensation disclosures            
Options granted (in shares)     1,721,748      
Restricted Stock            
Stock-based compensation disclosures            
Shares granted     364,549      
Issued (in dollars per share) | $ / shares     $ 29.57      
2013 Plan            
Stock-based compensation disclosures            
Shares authorized           1,057,692
Shares reserved for future awards         6,317,769  
2013 Plan | Stock options            
Stock-based compensation disclosures            
Expiration period     10 years      
2013 Plan | Performance based awards            
Stock-based compensation disclosures            
Number of awards with performance vesting criteria | item     1      
2015 Plan            
Stock-based compensation disclosures            
Increase to number of shares authorized 2,507,552          
2015 Employee Stock Purchase Plan            
Stock-based compensation disclosures            
Increase to number of shares authorized 626,888          
Shares reserved for future awards     2,137,127 1,630,199    
Maximum | 2013 Plan | Stock options            
Stock-based compensation disclosures            
Vesting period     4 years      
Maximum | 2015 Plan            
Stock-based compensation disclosures            
Shares reserved for future awards     2,923,076      
Percent of shares outstanding reserved for future awards (as a percent)     4.00%      
Maximum | 2015 Employee Stock Purchase Plan            
Stock-based compensation disclosures            
Shares reserved for future awards     769,230      
Percent of shares outstanding reserved for future awards (as a percent)     1.00%      
Minimum | 2013 Plan | Stock options            
Stock-based compensation disclosures            
Vesting period     1 year      
Chief Medical Officer | Stock options            
Stock-based compensation disclosures            
Options granted (in shares)   120,000        
Chief Medical Officer | Restricted Stock Units (RSUs)            
Stock-based compensation disclosures            
Shares granted   20,000        
Common Stock | Stock options            
Stock-based compensation disclosures            
Shares reserved for future awards     280,000 175,000    
Common Stock | 2013 Plan | Stock options            
Stock-based compensation disclosures            
Shares reserved for future awards     174,362 312,342    
Common Stock | 2015 Plan            
Stock-based compensation disclosures            
Shares reserved for future awards     5,599,450 4,061,357    
Common Stock | 2015 Plan | Stock options            
Stock-based compensation disclosures            
Shares reserved for future awards     3,839,345 4,254,357