Stock-Based Compensation (Tables)

6 Months Ended

Mar. 31, 2024

Share-based Compensation

Schedule of stock-based compensation expense

	Three months ended March 31,				Six months ended March 31,
	2024		2023		2024		2023
Research and development	$	236,960	$	322,268	$	468,376	$	612,924
General and administrative		1,073,547		1,061,137		2,114,742		2,162,874
	$	1,310,507	$	1,383,405	$	2,583,118	$	2,775,798

Schedule of performance-based stock units activity

				Weighted
				Average
	Number	Exercise		Remaining
	of	Price		Contractual	Aggregate
	PSUs	Per PSU		Term (Years)	Intrinsic Value
Balance at October 1, 2023	123	$	999.40
Forfeitures	—		—
Balance at March 31, 2024	123	$	999.40	0.3	$	—
Exercisable at March 31, 2024	123	$	999.40	0.3	$	—
Vested and expected to vest at March 31, 2024	123	$	999.40	0.3	$	—

Employee Stock Option [Member]

Share-based Compensation

Schedule of stock option activity

				Weighted
				Average
		Weighted		Remaining
	Number of	Average		Contractual	Aggregate
	Shares	Exercise Price		Term (Years)	Intrinsic Value
Balance at October 1, 2023	1,197,774	$	28.72
Granted	799,729		6.70
Forfeited	(29,605)		27.93
Expired	(8,333)		33.60
Balance at March 31, 2024	1,959,565	$	19.72	8.2	$	4,219,550
Exercisable at March 31, 2024	875,865	$	27.62	7.0	$	383,313
Vested and expected to vest at March 31, 2024	1,959,565	$	19.72	8.2	$	4,219,550

Schedule of option assumptions

	Six months ended March 31,
	2024		2023
Risk-free interest rate	4.3	%	3.7	%
Expected term (years)	6.0		5.7
Expected volatility	131.3	%	112.4	%
Expected dividend yield	—		—

Performance-based stock options

Share-based Compensation

Schedule of stock option activity

				Weighted
				Average
		Weighted		Remaining
	Number of	Average		Contractual	Aggregate
	Shares	Exercise Price		Term (Years)	Intrinsic Value
Balance at October 1, 2023	35,000	$	28.80
Granted	634,000		6.78
Balance at March 31, 2024	669,000	$	7.93	9.9	$	3,271,440
Exercisable at March 31, 2024	35,000	$	28.80	7.7	$	—
Vested and expected to vest at March 31, 2024	669,000	$	7.93	9.9	$	3,271,440

Schedule of option assumptions

	Six months ended March 31,
	2024		2023
Risk-free interest rate	4.3	%	3.8	%
Expected term (years)	10.0		10.0
Expected volatility	125.6	%	91.3	%
Expected dividend yield	—		—