CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Operating activities
Net loss	$ (52,179)	$ (52,764)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	6,376	4,611
Depreciation and amortization	457	350
Non-cash interest expense and amortization of debt issuance costs	3,061
Non-cash rent expense	94	(65)
Change in fair value of embedded derivative liability	(50)
Acquired IPR&D assets classified as investing activities	5,395
Changes in operating assets and liabilities:
Accounts receivable	(1,893)
Inventory	(2,570)
Prepaid expenses and other current assets	(186)	950
Deferred revenue	(6)
Other long-term assets	(99)	(6,661)
Accounts payable, accrued expenses and other liabilities	5,167	(53)
Net cash used in operating activities	(36,433)	(53,632)
Investing activities
Purchases of short-term investments	(69,644)	(39,479)
Maturities of short-term investments	92,675	112,128
Acquisition of IPR&D assets, including transaction costs	(4,520)
Purchases of property and equipment	(47)	(127)
Net cash provided by investing activities	18,464	72,522
Financing activities
Repayment of deferred royalty obligation	(1,351)
Proceeds from the exercise of stock options	553
Proceeds from issuance of common stock from ESPP	665	399
Net cash (used in) provided by financing activities	(133)	399
Effect of exchange rates on cash	86
Net (decrease) increase in cash, cash equivalents and restricted cash	(18,016)	19,289
Cash, cash equivalents and restricted cash at beginning of period	128,005	59,576
Cash, cash equivalents and restricted cash at end of period	109,989	$ 78,865
Supplemental disclosure of non-cash investing activities
Holdback payable associated with the acquisition, in accrued expenses	500
Transaction costs associated with the acquisition, in accounts payable	$ 375