The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Abeona Therapeutics Inc | COM | 00289Y107 | 10,880 | 849,979 | SH | SOLE | 849,979 | 0 | 0 | ||
| ACADIA Pharmaceuticals Inc | COM | 004225108 | 913 | 43,980 | SH | SOLE | 43,980 | 0 | 0 | ||
| ACADIA Pharmaceuticals Inc | COM | 004225108 | 10,380 | 500,000 | SH | Call | SOLE | 500,000 | 0 | 0 | |
| Achillion Pharmaceuticals Inc | COM | 00448Q201 | 5,829 | 1,583,954 | SH | SOLE | 1,583,954 | 0 | 0 | ||
| Acorda Therapeutics Inc | COM | 00484M106 | 983 | 50,000 | SH | SOLE | 50,000 | 0 | 0 | ||
| Adaptimmune Therapeutics Plc | SPONDS ADR | 00653A107 | 1,005 | 74,132 | SH | SOLE | 74,132 | 0 | 0 | ||
| Akorn Inc | COM | 009728106 | 454 | 35,000 | SH | SOLE | 35,000 | 0 | 0 | ||
| Allergan PLC | SHS | G0177J108 | 30,231 | 158,712 | SH | SOLE | 158,712 | 0 | 0 | ||
| ArQule Inc | COM | 04269E107 | 9,834 | 1,737,397 | SH | SOLE | 1,737,397 | 0 | 0 | ||
| AstraZeneca PLC | SPONSORED ADR | 046353108 | 7,648 | 193,279 | SH | SOLE | 193,279 | 0 | 0 | ||
| Audentes Therapeutics Inc | COM | 05070R104 | 21,425 | 541,172 | SH | SOLE | 541,172 | 0 | 0 | ||
| Bausch Health Cos Inc | COM | 071734107 | 14,003 | 545,500 | SH | SOLE | 545,500 | 0 | 0 | ||
| BioMarin Pharmaceutical Inc | COM | 09061G101 | 29,091 | 300,000 | SH | Call | SOLE | 300,000 | 0 | 0 | |
| Cara Therapeutics Inc | COM | 140755109 | 17,658 | 737,303 | SH | SOLE | 737,303 | 0 | 0 | ||
| Catalyst Biosciences Inc | COM NEW | 14888D208 | 9,622 | 892,579 | SH | SOLE | 892,579 | 0 | 0 | ||
| Chiasma Inc | COM | 16706W102 | 2,292 | 636,646 | SH | SOLE | 636,646 | 0 | 0 | ||
| Clearside Biomedical Inc | COM | 185063104 | 1,113 | 181,011 | SH | SOLE | 181,011 | 0 | 0 | ||
| Cymabay Therapeutics Inc | COM | 23257D103 | 10,068 | 908,664 | SH | SOLE | 908,664 | 0 | 0 | ||
| Deciphera Pharmaceuticals Inc | COM | 24344T101 | 1,186 | 30,622 | SH | SOLE | 30,622 | 0 | 0 | ||
| Dova Pharmaceuticals Inc | COM | 25985T102 | 21,534 | 1,026,906 | SH | SOLE | 1,026,906 | 0 | 0 | ||
| Eli Lilly & Co | COM | 532457108 | 5,366 | 50,000 | SH | Put | SOLE | 50,000 | 0 | 0 | |
| Endocyte Inc | COM | 29269A102 | 11,624 | 654,532 | SH | SOLE | 654,532 | 0 | 0 | ||
| Exelixis Inc | COM | 30161Q104 | 30,745 | 1,735,030 | SH | SOLE | 1,735,030 | 0 | 0 | ||
| FibroGen Inc | COM | 31572Q808 | 3,063 | 50,414 | SH | SOLE | 50,414 | 0 | 0 | ||
| Foamix Pharmaceuticals Ltd | SHS | M46135105 | 4,282 | 747,308 | SH | SOLE | 747,308 | 0 | 0 | ||
| Global Blood Therapeutics Inc | COM | 37890U108 | 20,871 | 549,231 | SH | SOLE | 549,231 | 0 | 0 | ||
| Heron Therapeutics Inc | COM | 427746102 | 2,844 | 89,849 | SH | SOLE | 89,849 | 0 | 0 | ||
| Immune Design Corp | COM | 45252L103 | 146 | 42,304 | SH | SOLE | 42,304 | 0 | 0 | ||
| Immunomedics Inc | COM | 452907108 | 29,132 | 1,398,577 | SH | SOLE | 1,398,577 | 0 | 0 | ||
| Insmed Inc | COM PAR $.01 | 457669307 | 9,385 | 464,159 | SH | SOLE | 464,159 | 0 | 0 | ||
| Insmed Inc | COM PAR $.01 | 457669307 | 5,055 | 250,000 | SH | Put | SOLE | 250,000 | 0 | 0 | |
| Iovance Biotherapeutics Inc | COM | 462260100 | 3,336 | 296,500 | SH | SOLE | 296,500 | 0 | 0 | ||
| Keryx Biopharmaceuticals Inc | COM | 492515101 | 680 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
| Kura Oncology Inc | COM | 50127T109 | 5,452 | 311,536 | SH | SOLE | 311,536 | 0 | 0 | ||
| Madrigal Pharmaceuticals Inc | COM | 558868105 | 857 | 4,000 | SH | SOLE | 4,000 | 0 | 0 | ||
| Magenta Therapeutics Inc | COM | 55910K108 | 1,802 | 150,000 | SH | SOLE | 150,000 | 0 | 0 | ||
| MediWound Ltd | ORD SHS | M68830104 | 1,064 | 173,076 | SH | SOLE | 173,076 | 0 | 0 | ||
| Molecular Templates Inc | COM | 608550109 | 569 | 105,600 | SH | SOLE | 105,600 | 0 | 0 | ||
| Mylan NV | SHS EURO | N59465109 | 25,466 | 695,788 | SH | SOLE | 695,788 | 0 | 0 | ||
| Nektar Therapeutics | COM | 640268108 | 7,803 | 128,000 | SH | SOLE | 128,000 | 0 | 0 | ||
| Neos Therapeutics Inc | COM | 64052L106 | 1,511 | 311,502 | SH | SOLE | 311,502 | 0 | 0 | ||
| OncoMed Pharmaceuticals Inc | COM | 68234X102 | 1,346 | 634,715 | SH | SOLE | 634,715 | 0 | 0 | ||
| OncoSec Medical Inc | COM NEW | 68234L207 | 1,944 | 1,388,824 | SH | SOLE | 1,388,824 | 0 | 0 | ||
| Pfizer Inc | COM | 717081103 | 5,288 | 120,000 | SH | Put | SOLE | 120,000 | 0 | 0 | |
| ProQR Therapeutics NV | SHS EURO | N71542109 | 1,023 | 52,875 | SH | SOLE | 52,875 | 0 | 0 | ||
| Savara Inc | COM | 805111101 | 1,089 | 97,600 | SH | SOLE | 97,600 | 0 | 0 | ||
| Sesen Bio Inc | COM | 817763105 | 2,531 | 1,177,000 | SH | SOLE | 1,177,000 | 0 | 0 | ||
| SPDR S&P Biotech ETF | S&P BIOTECH | 78464A870 | 95,870 | 1,000,000 | SH | Put | SOLE | 1,000,000 | 0 | 0 | |
| Stemline Therapeutics Inc | COM | 85858C107 | 9,662 | 582,070 | SH | SOLE | 582,070 | 0 | 0 | ||
| Sutro Biopharma Inc | COM | 869367102 | 3,474 | 231,613 | SH | SOLE | 25,929 | 0 | 0 | ||
| Synergy Pharmaceuticals Inc | COM NEW | 871639308 | 1,269 | 746,200 | SH | SOLE | 746,200 | 0 | 0 | ||
| TG Therapeutics Inc | COM | 88322Q108 | 2,492 | 445,000 | SH | SOLE | 445,000 | 0 | 0 | ||
| TherapeuticsMD Inc | COM | 88338N107 | 8,575 | 1,307,100 | SH | SOLE | 1,307,100 | 0 | 0 | ||
| Vaccinex Inc | COM | 918640103 | 124 | 17,047 | SH | SOLE | 17,047 | 0 | 0 | ||
| Viking Therapeutics Inc | COM | 92686J106 | 5,709 | 327,730 | SH | SOLE | 327,730 | 0 | 0 | ||
| Zosano Pharma Corp | COM NEW | 98979H202 | 4,228 | 1,033,759 | SH | SOLE | 1,033,759 | 0 | 0 | ||