The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abeona Therapeutics Inc COM 00289Y107 5,302 369,500 SH   SOLE   369,500 0 0
Adverum Biotechnologies Inc COM 00773U108 2,907 501,183 SH   SOLE   501,183 0 0
Allergan PLC SHS G0177J108 41,840 248,620 SH   SOLE   248,620 0 0
Akorn Inc COM 009728106 9,439 504,503 SH   SOLE   504,503 0 0
Arrowhead Pharmaceuticals Inc COM 04280A100 8,033 1,114,097 SH   SOLE   1,114,097 0 0
AstraZeneca PLC SPONSORED ADR 046353108 16,925 484,000 SH   SOLE   484,000 0 0
BioMarin Pharmaceutical Inc COM 09061G101 21,016 259,235 SH   SOLE   259,235 0 0
BioMarin Pharmaceutical Inc COM 09061G101 8,731 107,700 SH Call SOLE   107,700 0 0
Bristol-Myers Squibb Co COM 110122108 21,657 342,399 SH   SOLE   342,399 0 0
Cara Therapeutics Inc COM 140755109 4,346 351,050 SH   SOLE   351,050 0 0
Cymabay Therapeutics Inc COM 23257D103 11,076 852,686 SH   SOLE   852,686 0 0
Catalyst Biosciences Inc COM NEW 14888D208 13,896 538,624 SH   SOLE   538,624 0 0
Cellectis SA SPONSORED ADS 15117K103 10,485 332,754 SH   SOLE   332,754 0 0
Clovis Oncology Inc COM 189464100 12,809 242,600 SH Call SOLE   242,600 0 0
Corcept Therapeutics Inc COM 218352102 17,193 1,045,196 SH   SOLE   1,045,196 0 0
Dova Pharmaceuticals Inc COM 25985T102 15,411 568,243 SH   SOLE   568,243 0 0
FibroGen Inc COM 31572Q808 6,971 150,888 SH   SOLE   150,888 0 0
Homology Medicines Inc COM 438083107 243 13,000 SH   SOLE   13,000 0 0
Global Blood Therapeutics Inc COM 37890U108 15,222 315,147 SH   SOLE   315,147 0 0
Heron Therapeutics Inc COM 427746102 11,288 409,000 SH   SOLE   409,000 0 0
Immunomedics Inc COM 452907108 15,799 1,081,410 SH   SOLE   1,081,410 0 0
Insmed Inc COM PAR $.01 457669307 20,685 918,523 SH   SOLE   918,523 0 0
Kura Oncology Inc COM 50127T109 6,599 351,955 SH   SOLE   351,955 0 0
Madrigal Pharmaceuticals Inc COM 558868105 4,231 36,226 SH   SOLE   36,226 0 0
Menlo Therapeutics Inc COM 586858102 2,786 74,142 SH   SOLE   74,142 0 0
Mylan NV SHS EURO N59465109 10,745 261,000 SH   SOLE   261,000 0 0
NewLink Genetics Corp COM 651511107 3,625 500,000 SH Call SOLE   500,000 0 0
OncoSec Medical Inc COM NEW 68234L207 3,881 2,064,297 SH   SOLE   2,064,297 0 0
Pacira Pharmaceuticals Inc/DE COM 695127100 14,909 478,620 SH   SOLE   478,620 0 0
Perrigo Co PLC SHS G97822103 4,646 55,748 SH   SOLE   55,748 0 0
Sage Therapeutics Inc COM 78667J108 12,600 78,227 SH   SOLE   78,227 0 0
Seattle Genetics Inc COM 812578102 18,998 362,974 SH   SOLE   362,974 0 0
Sangamo Therapeutics Inc COM 800677106 14,941 786,376 SH   SOLE   786,376 0 0
Shire PLC SPONSORED ADR 82481R106 20,846 139,543 SH   SOLE   139,543 0 0
Sol-Gel Technologies Ltd SHS M8694L103 5,334 517,873 SH   SOLE   517,873 0 0
Stemline Therapeutics Inc COM 85858C107 8,011 523,624 SH   SOLE   523,624 0 0
SPDR S&P Biotech ETF S&P BIOTECH 78464A870 175,460 2,000,000 SH Put SOLE   1,000,000 0 0
Xenon Pharmaceuticals Inc COM 98420N105 1,857 379,071 SH   SOLE   379,071 0 0
Zafgen Inc COM 98885E103 2,992 401,558 SH   SOLE   401,558 0 0
Zosano Pharma Corp COM NEW 98979H202 3,528 700,000 SH   SOLE   700,000 0 0