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CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY - USD ($)
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income
Accumulated Deficit
Balance at Dec. 31, 2019 $ 54,583,896 $ 26,562 $ 163,067,773 $ (10,321) $ (108,500,118)
Balance, Shares at Dec. 31, 2019   26,562,178      
Stock-based compensation 10,480,782   10,480,782    
Exercise of stock options $ 2,203,061 $ 454 2,202,607    
Exercise of stock options, Shares 454,497 454,497      
Issuance of common stock from public offerings, net of underwriter commissions and fees $ 56,682,236 $ 3,017 56,679,219    
Issuance of common stock from public offerings, net of underwriter discounts, Shares   3,016,901      
Issuance of common stock upon cashless exercise of warrants, net of shares withheld $ 278 (278)    
Issuance of common stock upon exercise of warrants, net, Shares   278,179      
Restricted stock awards 17 $ 57 (40)    
Restricted stock award, Shares   56,665      
Repurchase of restricted stock awards (271,051) $ (17) (271,034)    
Repurchase of restricted stock awards, Shares   (17,054)      
Stock Issued During Period, Shares, Restricted Stock Award, Gross   56,665      
Unrealized gains from available-for-sale securities 17,452     17,452  
Net loss (44,784,921)       (44,784,921)
Balance at Dec. 31, 2020 78,911,472 $ 30,351 232,159,029 (7,131) (153,285,039)
Balance, Shares at Dec. 31, 2020   30,351,366      
Issuance of common stock from ATM offering, net of sales agent commission and fees, Shares   1,383,887      
Issuance of common stock from ATM offering, net of sales agent commission and fees, Amount 17,384,668 $ 1,384 17,383,284    
Stock-based compensation 11,515,584 11,515,584    
Exercise of stock options $ 2,598,782 $ 382 2,598,400    
Exercise of stock options, Shares 382,219 382,219      
Issuance of common stock upon exercise of warrants, net, Shares 0        
Restricted stock award, Shares   131,667      
Issuance of common stock upon exercise of warrants, net, Shares   8,048      
Issuance of common stock upon exercise of warrants, net, Amount   $ 8 (8)    
Stock Issued During Period, Shares, Restricted Stock Award, Gross   131,667      
Restricted stock awards released, Amount $ 55 $ 132 (77)    
Restricted stock awards withheld at vesting to cover taxes, Shares   (54,691)      
Restricted stock awards withheld at vesting to cover taxes, Amount (750,183) $ (55) (750,128)    
Unrealized gains from available-for-sale securities (7,131)     (7,131)  
Net loss (44,161,175)       (44,161,175)
Balance at Dec. 31, 2021 $ 65,492,072 $ 32,202 $ 262,906,084 $ 0 $ (197,446,214)
Balance, Shares at Dec. 31, 2021   32,202,496