Share capital - Schedule of Stock Option Outstanding (Details) - $ / shares	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	8,549,322	9,220,326
Options outstanding, weighted average remaining contractual term	5 years 11 months 19 days
Number of options exercisable (in shares)	5,145,149
Options exercisable, weighted average remaining contractual term	5 years 2 months 26 days
0.00 - 10.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	1,116,075
Options outstanding, weighted average remaining contractual term	4 years 5 months 23 days
Number of options exercisable (in shares)	1,116,075
Options exercisable, weighted average remaining contractual term	4 years 5 months 23 days
0.00 - 10.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 0.00
0.00 - 10.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 10.00
10.01 - 20.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	2,668,814
Options outstanding, weighted average remaining contractual term	4 years 11 months 8 days
Number of options exercisable (in shares)	1,787,295
Options exercisable, weighted average remaining contractual term	4 years 8 months 26 days
10.01 - 20.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 10.01
10.01 - 20.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 20.00
20.01 - 30.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	1,886,852
Options outstanding, weighted average remaining contractual term	5 years 6 months 10 days
Number of options exercisable (in shares)	1,461,424
Options exercisable, weighted average remaining contractual term	5 years 4 months 6 days
20.01 - 30.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 20.01
20.01 - 30.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 30.00
30.01 - 40.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	331,417
Options outstanding, weighted average remaining contractual term	6 years 6 months 21 days
Number of options exercisable (in shares)	272,217
Options exercisable, weighted average remaining contractual term	6 years 6 months 14 days
30.01 - 40.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 30.01
30.01 - 40.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 40.00
40.01 - 60.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	1,200,783
Options outstanding, weighted average remaining contractual term	7 years 3 months 14 days
Number of options exercisable (in shares)	274,740
Options exercisable, weighted average remaining contractual term	7 years 2 months 15 days
40.01 - 60.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 40.01
40.01 - 60.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 60.00
60.01 - 100.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	871,555
Options outstanding, weighted average remaining contractual term	8 years 2 months 4 days
Number of options exercisable (in shares)	227,804
Options exercisable, weighted average remaining contractual term	8 years 1 month 17 days
60.01 - 100.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 60.01
60.01 - 100.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 100.00
100.01 - 160.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	462,606
Options outstanding, weighted average remaining contractual term	9 years 3 months
Number of options exercisable (in shares)	5,594
Options exercisable, weighted average remaining contractual term	8 years 10 months 6 days
100.01 - 160.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 100.01
100.01 - 160.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 160.00
160.01 - 220.00
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Number of options outstanding (in shares)	11,220
Options outstanding, weighted average remaining contractual term	9 years 5 months 1 day
Number of options exercisable (in shares)	0
Options exercisable, weighted average remaining contractual term	0 years
160.01 - 220.00 | Minimum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 160.01
160.01 - 220.00 | Maximum
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Exercise price (in usd per share)	$ 220.00