Cash and Cash equivalents and Short-term investments - Additional Information (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Cash and Cash Equivalents [Line Items]
Estimated fair value of short-term investments	$ 728,906	$ 607,905
Fair value, inputs, level 1
Cash and Cash Equivalents [Line Items]
Estimated fair value of short-term investments	$ 624,083	$ 607,905