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Share Capital (Tables)
12 Months Ended
Dec. 31, 2019
Share-based Compensation, Allocation and Classification in Financial Statements [Abstract]  
Schedule of Share Capital
Share capital is composed as follows:
Issued and outstanding
Number of shares
December 31,
 20192018
Ordinary shares no par value99,528,435  93,254,185  
Schedule of Fair Value Assumptions Used for All Equity Based Awards Estimated Using Black-Scholes Option Pricing Model
The fair value of share-based awards was estimated using the Black-Scholes model for all equity grants. For market condition awards, the Company also applied the Monte-Carlo simulation model, with the following underlying assumptions:
Year ended December 31,
 201920182017
Stock Option Plans
Expected term (years)
5.50-6.00
5.50-6.25
5.50-6.25
Expected volatility
55%-61%
52%-55%
57%-59%
Risk-free interest rate
1.73%-2.40%
2.70%-2.99%
1.97%-2.23%
Dividend yield0.00 %0.00 %0.00 %
ESPP
Expected term (years)0.500.500.50
Expected volatility
44%-62%
45%-53%
76%-82%
Risk-free interest rate
2.10%-2.51%
1.61%-2.14%
0.62%-1.13%
Dividend yield0.00 %0.00 %0.00 %
Schedule of Stock Options to Purchase Ordinary Shares
A summary of the status of the Company’s options to purchase ordinary shares as of December 31, 2019 and changes during the year ended on that date is presented below:
Year ended December 31, 2019
 
Number of
options
Weighted
average
exercise
price
Aggregate
intrinsic
value
Outstanding at beginning of year14,438,215  $13.56  
Granted1,552,987  50.45  
Exercised(5,466,170) 10.83  
Forfeited and cancelled(174,222) 22.11  
Outstanding at end of year10,350,810  $20.40  $661,150  
Exercisable options3,217,923  $15.55  $221,146  
Schedule of RSUs
A summary of the status of the Company’s RSUs as of December 31, 2019 and changes during the year ended on that date is presented below:
 Year ended December 31, 2019
 
Number of
RSUs
Weighted
average
grant date
fair value
price
Aggregate
intrinsic
value
Unvested at beginning of year1,613,197  $14.04  
Granted634,694  52.28  
Vested(740,714) 13.47  
Forfeited and cancelled(32,782) 37.84  
Unvested at end of year1,474,395  $30.26  $124,247  
Schedule of Equity-Based Compensation Expenses Related to Company's Equity-Based Awards The total equity-based compensation expense related to all of the Company’s equity-based awards recognized for the years ended December 31, 2019, 2018 and 2017, was comprised as follows:
Year ended December 31,
 201920182017
Cost of revenues$2,231  $1,261  $467  
Research, development and clinical trials7,570  4,709  3,587  
Sales and marketing11,897  7,393  3,784  
General and administrative30,718  26,483  19,278  
Total share-based compensation expense$52,416  $39,846  $27,116  
Schedule of Stock Option Outstanding
The options outstanding as of December 31, 2019 are as follows:
Exercise price
Number
of options
outstanding
Weighted
average
remaining
contractual
term
Number
of options
exercisable
Weighted
average
remaining
contractual
term
$ (years) (years)
0.23 - 10.00
2,256,916  6.15984,380  4.87
10.01 - 20.00
3,205,758  6.83869,058  5.84
20.01 - 30.00
2,933,518  7.41,225,951  6.57
30.01 - 40.00
424,414  8.56138,534  8.47
40.01 - 50.00
1,347,064  9.29—  
50.01 - 60.00
44,380  9.39—  
60.01 - 90.00
138,760  9.7—  
 10,350,810  7.283,217,923  5.94