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Selected Quarterly Financial Information (Unaudited) - Summary of Selected Quarterly Financial Information (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Selected Quarterly Financial Information [Abstract]                      
Net revenues $ 30,242 $ 21,674 $ 17,919 $ 13,053 $ 12,383 $ 8,953 $ 6,543 $ 5,208 $ 82,888 $ 33,087 $ 15,490
Gross profit 19,268 10,556 1,710 5,071 6,079 3,294 1,793 1,311 36,606 12,477 5,454
Operating loss (17,877) (28,265) (37,237) (31,938) (30,606) (24,238) (27,206) (21,946) (115,317) (103,996) (80,156)
Net loss $ (22,168) $ (33,628) $ (40,612) $ (35,437) $ (32,928) $ (26,023) $ (29,357) $ (23,273) $ (131,845) $ (111,581) $ (80,682)
Basic and diluted net loss per ordinary share $ (0.26) $ (0.39) $ (0.48) $ (0.42) $ (0.39) $ (2.09) $ (2.36) $ (1.77) $ (1.54) $ (3.67) $ (6.46)
Weighted average number of ordinary shares used in computing basic and diluted net loss per share 86,760,316 85,774,874 85,274,683 84,397,164 83,607,037 12,431,586 12,427,442 13,140,321 85,558,448 30,401,603 12,490,017