October 3, 2019

Craig Cook
Chief Executive Officer
Midatech Pharma PLC
Oddfellows House
19 Newport Road
Cardiff, United Kingdom
CF24 OAA

       Re: Midatech Pharma PLC
           Registration Statement on Form F-3
           Filed September 23, 2019
           File No. 333-233901

Dear Dr. Cook:

       We have limited our review of your registration statement to those
issues we have
addressed in our comments. In some of our comments, we may ask you to provide
us with
information so we may better understand your disclosure.

       Please respond to this letter by amending your registration statement
and providing the
requested information. If you do not believe our comments apply to your facts
and
circumstances or do not believe an amendment is appropriate, please tell us why
in your
response.

       After reviewing any amendment to your registration statement and the
information you
provide in response to these comments, we may have additional comments.

Registration Statement on Form F-3

General

1.     Please refer to Section 7.6 of Exhibit 4.2. We note that the depositary
is entitled to refer
       any dispute or difference for final settlement by arbitration in
accordance with the
       Commercial Arbitration Rules of the American Arbitration Association.
Please revise the
       prospectus to describe the arbitration provision and to disclose the
impact of this provision
       on holders of your ADSs for claims under the federal securities laws.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.
 Craig Cook
Midatech Pharma PLC
October 3, 2019
Page 2

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.

       Please contact Donald Field at 202-551-3680 or Justin Dobbie at
202-551-3469 with
any questions.



FirstName LastNameCraig Cook                               Sincerely,
Comapany NameMidatech Pharma PLC
                                                           Division of
Corporation Finance
October 3, 2019 Page 2                                     Office of Life
Sciences
FirstName LastName