Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Total revenues	$ 36,935	$ 28,895	$ 5,027
Operating expenses:
Cost of revenues	(28,581)	(13,148)	(766)
Loss on inventory commitments	(4,317)
Research and development expenses	(14,263)	(12,630)	(15,102)
Selling, general and administrative expenses	(45,264)	(51,645)	(55,285)
Total operating expenses	(92,425)	(77,423)	(71,153)
Loss from operations	(55,490)	(48,528)	(66,126)
Other income (expense):
Other income, net	571	469	1,187
Interest expense, net	(698)	(901)	(1,649)
Loss on extinguishment of debt			(2,757)
Loss before income taxes	(55,617)	(48,960)	(69,345)
Income tax expense	(1,568)	(490)	(139)
Net loss	$ (57,185)	$ (49,450)	$ (69,484)
Loss per share
Basic loss ($ per share)	$ (21.32)	$ (28.52)	$ (135.23)
Diluted loss ($ per share)	$ (21.32)	$ (28.52)	$ (135.23)
Weighted average number of shares:
Basic (in shares)	2,681,968	1,733,978	513,804
Diluted (in shares)	2,681,968	1,733,978	513,804
Product revenue, net
Revenues:
Total revenues	$ 34,742	$ 23,386	$ 108
Collaboration revenue
Revenues:
Total revenues	926	3,830	2,756
Research premium and grant revenue
Revenues:
Total revenues	$ 1,267	$ 1,679	$ 2,163