Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Ordinary shares	Additional paid in capital	Accumulated other comprehensive income	Accumulated deficit	Total
Stockholders' equity, beginning balance at Dec. 31, 2020	$ 8	$ 579,326	$ 27	$ (546,226)	$ 33,135
Stockholders' equity, beginning balance (in shares) at Dec. 31, 2020	843
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 6	37,234			37,240
Issuance of ordinary shares (in shares)	572
Shares issued in connection with the vesting of restricted share units		1			1
Shares issued in connection with the vesting of restricted share units (in shares)	2
Equity transaction costs		(2,325)			(2,325)
Stock-based compensation expense		921			921
Net loss				(13,981)	(13,981)
Stockholders' equity, ending balance at Mar. 31, 2021	$ 14	615,157	27	(560,207)	54,991
Stockholders' equity, ending balance (in shares) at Mar. 31, 2021	1,417
Stockholders' equity, beginning balance at Dec. 31, 2020	$ 8	579,326	27	(546,226)	33,135
Stockholders' equity, beginning balance (in shares) at Dec. 31, 2020	843
Consolidated Statements of Changes in Stockholders' Equity
Net loss					(36,387)
Stockholders' equity, ending balance at Sep. 30, 2021	$ 22	645,854	27	(582,613)	63,290
Stockholders' equity, ending balance (in shares) at Sep. 30, 2021	2,173
Stockholders' equity, beginning balance at Mar. 31, 2021	$ 14	615,157	27	(560,207)	54,991
Stockholders' equity, beginning balance (in shares) at Mar. 31, 2021	1,417
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 6	26,133			26,139
Issuance of ordinary shares (in shares)	573
Equity transaction costs		(992)			(992)
Stock-based compensation expense		817			817
Net loss				(11,754)	(11,754)
Stockholders' equity, ending balance at Jun. 30, 2021	$ 20	641,115	27	(571,961)	69,201
Stockholders' equity, ending balance (in shares) at Jun. 30, 2021	1,990
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 2	4,302			4,304
Issuance of ordinary shares (in shares)	157
Shares issued in connection with the vesting of restricted share units		1			1
Shares issued in connection with the vesting of restricted share units (in shares)	1
Equity transaction costs		(343)			(343)
Equity transaction costs, shares issued (in shares)	25
Stock-based compensation expense		779			779
Net loss				(10,652)	(10,652)
Stockholders' equity, ending balance at Sep. 30, 2021	$ 22	645,854	27	(582,613)	63,290
Stockholders' equity, ending balance (in shares) at Sep. 30, 2021	2,173
Stockholders' equity, beginning balance at Dec. 31, 2021	$ 23	648,976	27	(595,676)	53,350
Stockholders' equity, beginning balance (in shares) at Dec. 31, 2021	2,269
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 2	2,219			2,221
Issuance of ordinary shares (in shares)	198
Shares issued in connection with the vesting of restricted share units (in shares)	3
Equity transaction costs		(127)			(127)
Stock-based compensation expense		1,000			1,000
Net loss				(11,819)	(11,819)
Stockholders' equity, ending balance at Mar. 31, 2022	$ 25	652,068	27	(607,495)	44,625
Stockholders' equity, ending balance (in shares) at Mar. 31, 2022	2,470
Stockholders' equity, beginning balance at Dec. 31, 2021	$ 23	648,976	27	(595,676)	53,350
Stockholders' equity, beginning balance (in shares) at Dec. 31, 2021	2,269
Consolidated Statements of Changes in Stockholders' Equity
Net loss					(34,407)
Stockholders' equity, ending balance at Sep. 30, 2022	$ 30	655,649	27	(630,083)	25,623
Stockholders' equity, ending balance (in shares) at Sep. 30, 2022	3,021
Stockholders' equity, beginning balance at Mar. 31, 2022	$ 25	652,068	27	(607,495)	44,625
Stockholders' equity, beginning balance (in shares) at Mar. 31, 2022	2,470
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 1	817			818
Issuance of ordinary shares (in shares)	114
Shares issued in connection with the vesting of restricted share units		1			1
Equity transaction costs		(82)			(82)
Stock-based compensation expense		317			317
Net loss				(11,074)	(11,074)
Stockholders' equity, ending balance at Jun. 30, 2022	$ 26	653,121	27	(618,569)	34,605
Stockholders' equity, ending balance (in shares) at Jun. 30, 2022	2,584
Consolidated Statements of Changes in Stockholders' Equity
Issuance of ordinary shares	$ 4	2,161			2,165
Issuance of ordinary shares (in shares)	432
Shares issued in connection with the vesting of restricted share units (in shares)	5
Equity transaction costs		(82)			(82)
Stock-based compensation expense		449			449
Net loss				(11,514)	(11,514)
Stockholders' equity, ending balance at Sep. 30, 2022	$ 30	$ 655,649	$ 27	$ (630,083)	$ 25,623
Stockholders' equity, ending balance (in shares) at Sep. 30, 2022	3,021