Share-Based Payments - Share-Based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Share-Based Payments
Share-based compensation expense	$ 498	$ 779	$ 1,832	$ 2,517
Research and development
Share-Based Payments
Share-based compensation expense	63	96	224	435
Selling, general and administrative
Share-Based Payments
Share-based compensation expense	$ 435	$ 683	$ 1,608	$ 2,082