Price of a Commitment share.

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- Definition

The cash inflow from the additional capital contribution to the entity before deduction of issuance expenses.

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n/a

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Number of additional countries rights are distributed through Named Patient Usage Program.

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Number of countries, exclusive rights are distributed.

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The value of shares available for sale remains unsold.

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Number of commitment shares issued during the period.

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- Definition

Threshold limit of commitment under single regular share purchase.

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Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage. Excludes amount for disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates.

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The cash inflow from the additional capital contribution to the entity.

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- Definition

Cash received on stock transaction after deduction of issuance costs.

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No definition available.

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- Definition

Price of a single share of a number of saleable stocks of a company.

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- Definition

Number of new stock issued during the period.

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Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.

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Organization and Business Activities (Details)			1 Months Ended	3 Months Ended						9 Months Ended
Organization and Business Activities (Details)	Nov. 10, 2022 USD ($)	Nov. 02, 2022 USD ($)	Sep. 30, 2021 USD ($) $ / shares shares	Sep. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Sep. 30, 2021 USD ($) $ / shares	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Sep. 30, 2022 USD ($) shares	Sep. 30, 2021 USD ($) $ / shares	Jul. 31, 2022 country	Jul. 13, 2022 country	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Liquidity
Number of countries, exclusive rights are distributed. \| country												9	9
Number of additional countries rights are distributed \| country												5	5
Cash and cash equivalents and restricted cash			$ 52,174,000	$ 14,768,000			$ 52,174,000			$ 14,768,000	$ 52,174,000			$ 47,834,000	$ 41,590,000
Proceeds from at-the-market facility										$ 3,080,000	$ 42,280,000
Shares issued				$ 2,165,000	$ 818,000	$ 2,221,000	$ 4,304,000	$ 26,139,000	$ 37,240,000
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares
Liquidity
Number of shares issued \| shares										320,000
Net proceeds from sale of stock										$ 4,600,000
Commitment shares \| shares			25,298
Commitment share price \| $ / shares			$ 0.01				$ 0.01				$ 0.01
Regular purchase			$ 2,500,000
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Minimum
Liquidity
Shares issued			200,000
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Maximum
Liquidity
Shares issued			$ 23,000,000.0
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $0.25 Per Share
Liquidity
Share price \| $ / shares			$ 0.25				0.25				0.25
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $0.25 Per Share \| Maximum
Liquidity
Number of shares issued \| shares			16,000
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $2.00 Per Share
Liquidity
Share price \| $ / shares			$ 50.00				50.00				50.00
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $2.00 Per Share \| Maximum
Liquidity
Number of shares issued \| shares			24,000
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $3.00 Per Share
Liquidity
Share price \| $ / shares			$ 75.00				$ 75.00				$ 75.00
Lincoln Park Capital Fund, LLC \| Purchase agreement \| Ordinary shares \| Share Price Not Below $3.00 Per Share \| Maximum
Liquidity
Number of shares issued \| shares			32,000
Open Market Sale Agreement \| Jefferies LLC \| Ordinary shares
Liquidity
Number of shares issued \| shares										1,249,898
Proceeds from at-the-market facility										$ 32,200,000
Aggregate gross sale proceeds for ordinary shares										$ 33,500,000
Subsequent Event \| Jefferies LLC \| At-the-market offering \| Maximum
Liquidity
Ordinary shares remained unsold	$ 8,000,000.0
Subsequent Event \| Lincoln Park Capital Fund, LLC \| Purchase agreement \| Maximum
Liquidity
Ordinary shares remained unsold		$ 18,500,000