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Significant Arrangements and License Agreements (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 12, 2021
Jul. 10, 2020
USD ($)
Dec. 31, 2020
USD ($)
Mar. 31, 2018
USD ($)
Mar. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2019
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2021
USD ($)
employee
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
May 31, 2021
USD ($)
License Agreement                        
Revenue accounted for under Topic 606                 $ 28,895 $ 5,027 $ 9,481  
Number of sales representatives | employee                 60      
Collaboration revenue - Upfront payment                        
License Agreement                        
Revenue accounted for under Topic 606                 $ 23,386 $ 108 1,538  
SIVEXTRO                        
License Agreement                        
Percentage of net product sales recognized 100.00%                      
Sunovion Pharmaceutics Canada, Inc. | Collaboration revenue - Upfront payment                        
License Agreement                        
Revenue accounted for under Topic 606       $ 1,000                
License Agreement | Sinovant Sciences, LTD | Collaboration revenue - Upfront payment                        
License Agreement                        
Revenue accounted for under Topic 606                     1,000  
License Agreement | Sinovant Sciences, LTD | Collaboration revenue - Variable consideration                        
License Agreement                        
Proceeds from license agreement, milestone                     $ 5,000  
License Agreement | Sunovion Pharmaceutics Canada, Inc. | NDS Approval                        
License Agreement                        
Revenue accounted for under Topic 606   $ 500                    
License Agreement | Sumitomo Pharmaceuticals (Suzhou)                        
License Agreement                        
Upfront payment                       $ 5,000
Notice period for termination of agreement                 180 days      
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Achievement of certain regulatory and commercial milestones                        
License Agreement                        
Maximum contingent milestone payment                       91,500
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Subsequent regulatory approval                        
License Agreement                        
Maximum contingent milestone payment                       $ 4,000
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Clinical trial application submission                        
License Agreement                        
Proceeds from license agreement, milestone               $ 1,500        
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | FDA approval                        
License Agreement                        
Revenue accounted for under Topic 606             $ 5,000          
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Approval of XENLETA                        
License Agreement                        
Revenue accounted for under Topic 606     $ 5,000                  
Remaining probable of achieving                 $ 1,000      
Additional revenue recognized                 3,000      
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Additional regulatory approvals and annual sales targets                        
License Agreement                        
Remaining milestone payments                 86,000      
License Agreement | Sumitomo Pharmaceuticals (Suzhou) | Collaboration revenue - Upfront payment                        
License Agreement                        
Revenue accounted for under Topic 606     $ 3,000     $ 1,000   $ 5,000        
Milestone achieved         $ 1,000              
Performance obligation                 $ 2,400