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Organization and Business Activities (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
May 31, 2021
USD ($)
shares
Nov. 30, 2020
employee
Sep. 30, 2020
employee
Mar. 31, 2021
USD ($)
$ / shares
shares
Jun. 30, 2021
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
Dec. 31, 2020
$ / shares
Jun. 30, 2019
USD ($)
Liquidity                
Percentage of lefamulin-treated patients 4.00%              
Percentage of moxifloxacin-treated patients 10.00%              
Percentage of TEASE's leading to discontinuation were subjects in both treatment arms 5.00%              
Cash, cash equivalents and short-term investments         $ 61,300      
Number of sales representatives | employee   60 15          
Proceeds from at-the-market facility         $ 37,970 $ 3,688    
Nominal value | $ / shares         $ 0.01   $ 0.01  
Jefferies LLC | At-the-market offering                
Liquidity                
Maximum aggregate gross proceeds under the sales agreement               $ 50,000
Proceeds from at-the-market facility         $ 26,100      
Net proceeds from sale of stock         $ 25,100      
Jefferies LLC | At-the-market offering | Ordinary Shares                
Liquidity                
Number of shares issued | shares         14,318,074      
Purchasers | Purchase agreement                
Liquidity                
Number of shares issued | shares       9,761,010        
Net proceeds from sale of stock       $ 23,400        
Proceeds from Issuance or Sale of Equity       $ 25,400        
Number of ordinary shares that can be purchased by warrant holders | shares       4,880,505        
Term       5 years        
Ordinary Share Warrants | Purchasers | Purchase agreement                
Liquidity                
Number of ordinary shares that can be purchased by warrant holders | shares       300,000        
Nominal value | $ / shares       $ 0.01        
Share and warrant price | $ / shares       2.4525        
Exercise price | $ / shares       $ 2.39        
Pre-Funded Warrants | Purchasers | Purchase agreement                
Liquidity                
Number of ordinary shares that can be purchased by warrant holders | shares       600,000        
Share and warrant price | $ / shares       $ 2.4425        
Exercise price | $ / shares       $ 0.01        
Open Market Sale Agreement | Jefferies LLC | Ordinary Shares                
Liquidity                
Number of shares issued | shares 5,925,699              
Proceeds from at-the-market facility $ 31,900              
Aggregate gross sale proceeds for ordinary shares 33,700              
Ordinary shares remained unsold 16,300              
Open Market Sale Agreement | Jefferies LLC | Ordinary Shares | Maximum                
Liquidity                
Aggregate gross sale proceeds for ordinary shares $ 50,000