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Significant Arrangements and License Agreements (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Jul. 10, 2020
USD ($)
Nov. 30, 2020
employee
Sep. 30, 2020
employee
Mar. 31, 2018
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2019
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
License Agreement                    
Revenue accounted for under Topic 606               $ 5,027 $ 9,481 $ 9,656
Number Of Sales Representatives | employee   60 15              
Collaboration revenue - Upfront payment                    
License Agreement                    
Revenue accounted for under Topic 606               108 1,538  
Sunovion Pharmaceutics Canada, Inc. | NDS Approval                    
License Agreement                    
Revenue accounted for under Topic 606 $ 500                  
Sunovion Pharmaceutics Canada, Inc. | Collaboration revenue - Upfront payment                    
License Agreement                    
Revenue accounted for under Topic 606       $ 1,000            
License Agreement | Collaboration revenue - Upfront payment                    
License Agreement                    
Revenue accounted for under Topic 606               $ 1,000    
License Agreement | Sinovant Sciences, LTD                    
License Agreement                    
Notice period for termination of agreement               180 days    
License Agreement | Sinovant Sciences, LTD | Achievement of certain regulatory and commercial milestones                    
License Agreement                    
Maximum contingent milestone payment         $ 91,500     $ 91,500    
License Agreement | Sinovant Sciences, LTD | Subsequent regulatory approval                    
License Agreement                    
Maximum contingent milestone payment         4,000     4,000    
License Agreement | Sinovant Sciences, LTD | Clinical trial application submission                    
License Agreement                    
Proceeds from license agreement, milestone             $ 1,500      
License Agreement | Sinovant Sciences, LTD | FDA approval                    
License Agreement                    
Revenue accounted for under Topic 606           $ 5,000        
License Agreement | Sinovant Sciences, LTD | Approval of XENLETA                    
License Agreement                    
Revenue accounted for under Topic 606         5,000          
License Agreement | Sinovant Sciences, LTD | Additional regulatory approvals and annual sales targets                    
License Agreement                    
Remaining milestone payments         86,500     $ 86,500    
License Agreement | Sinovant Sciences, LTD | Collaboration revenue - Upfront payment                    
License Agreement                    
Revenue accounted for under Topic 606       $ 5,000 $ 1,000       1,000  
License Agreement | Sinovant Sciences, LTD | Collaboration revenue - Variable consideration                    
License Agreement                    
Proceeds from license agreement, milestone                 $ 5,000