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Revenue (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Mar. 31, 2018
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Revenue          
Revenue accounted for under Topic 606   $ 1,291 $ 6,920 $ 2,567 $ 9,148
Product revenue, gross   8   400  
Sunovion Pharmaceutics Canada, Inc. | License Agreement          
Revenue          
Regulatory milestone payment received   500   500  
Collaboration revenue          
Revenue          
Revenue accounted for under Topic 606   616 5,051 768 6,051
Collaboration revenue - Upfront payment          
Revenue          
Revenue accounted for under Topic 606   (47) 1,445 61 1,445
Product revenue, gross   8   406  
Collaboration revenue - Upfront payment | Sinovant Sciences, LTD | License Agreement          
Revenue          
Revenue accounted for under Topic 606 $ 5,000       1,000
Collaboration revenue - Variable consideration          
Revenue          
Revenue accounted for under Topic 606   616 5,051 768 6,051
Collaboration revenue - Variable consideration | Sinovant Sciences, LTD | License Agreement          
Revenue          
Milestone payment received         5,000
Research premium          
Revenue          
Revenue accounted for under Topic 606   211 $ 424 802 1,168
Government grants          
Revenue          
Revenue accounted for under Topic 606   $ 511   $ 936 $ 484