Acquisition of Zavante (Details) - Zavante Therapeutics $ in Millions	Jul. 24, 2018 USD ($) shares
Acquisition of Zavante
Percentage of entity shares held by subsidiary	19.90%
In-process research and development expense	$ 32.0
Transaction costs	4.9
Net liabilities assumed	$ 0.2
Upfront Shares
Acquisition of Zavante
Business acquisition, shares issued or issuable \| shares	7,336,906
Expense from the fair value of shares issued in the acquisition	$ 26.9
Holdback Shares
Acquisition of Zavante
Business acquisition, shares issued or issuable \| shares	815,186
Merger Agreement \| Upfront Shares
Acquisition of Zavante
Holdback Shares, as a percentage of Upfront Shares	10.00%
Merger Agreement \| CONTEPO
Acquisition of Zavante
Threshold amount of annual net sales in one calendar year	$ 125.0
Merger Agreement \| CONTEPO \| Approval Milestone Payment
Acquisition of Zavante
Contingent consideration	25.0
Merger Agreement \| CONTEPO \| Net Sales Milestone Payments
Acquisition of Zavante
Contingent consideration	72.5
Merger Agreement \| CONTEPO \| Maximum \| Approval Milestone Payment
Acquisition of Zavante
Contingent consideration	$ 97.5

The amount of in-process research and development expense recorded in a business acquisition.

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The portion of in-process research and development expense which was recorded in a business acquisition that is associated with net liabilities assumed.

+ References

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The portion of in-process research and development expense which was recorded in a business acquisition that is associated with the fair value of shares issued.

+ References

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The portion of in-process research and development expense which was recorded in a business acquisition that is associated with transaction costs.

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Percentage of shares issued in business combination which will serve as a source for the satisfaction of indemnification and other obligations of the former Zavante stockholders and, subject to reduction in respect of these obligations, will be issued to the former Zavante stockholders following the first anniversary of the Closing.

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Percentage of entity shares held by subsidiary.

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The minimum amount of net sales in one calendar year in order to achieve the first commercial milestone as defined in the Merger Agreement.

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Number of shares of equity interests issued or issuable to acquire entity.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of liability recognized arising from contingent consideration in a business combination.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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