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Share-Based Payments - 2017 Share Incentive Plan (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Jul. 26, 2017
shares
Jun. 30, 2019
USD ($)
$ / shares
shares
Jun. 30, 2018
USD ($)
Jun. 30, 2019
USD ($)
item
$ / shares
shares
Jun. 30, 2018
USD ($)
Stock-Based Compensation Expense          
Share-based compensation expense | $       $ 3,728 $ 2,011
2017 Share Incentive Plan          
Options          
Outstanding at beginning of year (in shares)       2,398,425  
Granted (in shares)       2,218,300  
Forfeited (in shares)       (98,650)  
Outstanding at end of year (in shares)   4,518,075   4,518,075  
Vested and exercisable at end of year (in shares)   817,682   817,682  
Weighted average exercise price in $ per share          
Outstanding balance at beginning of year (in dollars per share) | $ / shares       $ 5.41  
Granted (in dollars per share) | $ / shares       1.91  
Forfeited (in dollars per share) | $ / shares       4.14  
Outstanding balance at end of year (in dollars per share) | $ / shares   $ 3.72   3.72  
Vested and exercisable balance at end of year (in dollars per share) | $ / shares   $ 6.03   $ 6.03  
Aggregate intrinsic value          
Aggregate intrinsic value, outstanding | $   $ 1,245   $ 1,245  
2017 Share Incentive Plan | Stock Options          
Share-Based Payments          
Vesting period       10 years  
Fair Value Assumptions          
Expected term of options (in years)       6 years 1 month 6 days  
Dividend yield (as a percent)       0.00%  
Weighted-average remaining contractual life       9 years 1 month 6 days  
Stock-Based Compensation Expense          
Share-based compensation expense | $   800 $ 300 $ 1,300 $ 700
Weighted-average grant date fair value (in dollars per share) | $ / shares       $ 1.12  
Unrecognized compensation expense          
Total unrecognized compensation related to unvested options | $   6,700   $ 6,700  
Recognition period       3 years 9 months 18 days  
2017 Share Incentive Plan | Stock Options | Minimum          
Fair Value Assumptions          
Expected volatility (as a percent)       61.40%  
Risk-free interest rate (as a percent)       2.34%  
Term of U.S. treasury securities used to estimate risk free interest rate       5 years  
2017 Share Incentive Plan | Stock Options | Maximum          
Fair Value Assumptions          
Expected volatility (as a percent)       61.80%  
Risk-free interest rate (as a percent)       2.58%  
Term of U.S. treasury securities used to estimate risk free interest rate       7 years  
2017 Share Incentive Plan | SARs          
Share-Based Payments          
Vesting period       10 years  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs")          
Share-Based Payments          
Vesting period       4 years  
Expiration period if drug is not approved       2 years  
Stock-Based Compensation Expense          
Share-based compensation expense | $   $ 57   $ 95  
Restricted Stock Units          
Restricted stock granted during the period       479,000  
Weighted average grant date fair value per share | $ / shares       $ 1.90  
Number of shares vested       256,709  
Number of shares outstanding   479,000   479,000  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Vesting period, year one          
Restricted Stock Units          
Percentage that vests during the period       25.00%  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Vesting subject to FDA approval of NDA for lefamulin          
Stock-Based Compensation Expense          
Share-based compensation expense | $       $ 0  
Restricted Stock Units          
Aggregate number of shares granted under the plan   371,550   371,550  
Weighted average grant date fair value per share | $ / shares       $ 6.13  
Number of shares outstanding   346,450   346,450  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Immediate vesting upon regulatory approval          
Restricted Stock Units          
Percentage that vests during the period       50.00%  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Vesting upon the one-year-anniversary of FDA approval          
Restricted Stock Units          
Percentage that vests during the period       50.00%  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Vesting subject to FDA approval of NDA for lefamulin and CONTEPO          
Stock-Based Compensation Expense          
Share-based compensation expense | $       $ 0  
Restricted Stock Units          
Aggregate number of shares granted under the plan   35,600   35,600  
Weighted average grant date fair value per share | $ / shares       $ 2.56  
2017 Share Incentive Plan | Restricted Stock Units ("RSUs") | Employees          
Share-Based Payments          
Number of vesting periods | item       3  
Vesting period       6 months  
Stock-Based Compensation Expense          
Share-based compensation expense | $   $ 300   $ 500  
Weighted-average grant date fair value (in dollars per share) | $ / shares       $ 2.16  
Restricted Stock Units          
Aggregate number of shares granted under the plan   834,300   834,300  
Number of shares outstanding   513,591   513,591  
2017 Share Incentive Plan | Ordinary Shares          
Share-Based Payments          
Number of shares authorized 3,000,000        
Additional shares authorized 3,438,990        
Shares available for grant   7,116,727   7,116,727  
2017 Share Incentive Plan | Ordinary Shares | Minimum          
Share-Based Payments          
Annual increase, to be added on the first day of each fiscal year (in shares) 2,000,000        
Annual increase, to be added on the first day of each fiscal year (as a percent) 4.00%