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Share-Based Payments - Inducement Awards Outside of the 2019 Inducement Plan (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
Jul. 31, 2018
Mar. 31, 2019
Mar. 31, 2018
Share-Based Payments      
Share-based compensation expense   $ 1,907 $ 1,244
Inducement Awards Outside of the 2019 Inducement Plan      
Share-Based Payments      
Share-based compensation expense   $ 109,000,000  
Additional disclosures      
Weighted-average remaining contractual life   9 years 3 months 18 days  
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option      
Share-Based Payments      
Vesting period 4 years    
Options exercise price (in dollars per share) $ 3.53 $ 2.05  
Exercise period 10 years    
Fair Value Assumptions      
Expected volatility (as a percent)   59.80%  
Expected term of options (in years)   6 years 1 month 6 days  
Risk-free interest rate (as a percent)   2.90%  
Dividend yield (as a percent)   0.00%  
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option | Chief Executive Officer      
Share-Based Payments      
Options granted during the period 850,000    
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option | Vesting period, year one      
Share-Based Payments      
Percentage that vests during the period 25.00%    
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option | Vesting period, years 2-4      
Share-Based Payments      
Percentage that vests during the period 75.00%    
Monthly vesting period 36 months    
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option | Upon receipt of FDA approval      
Share-Based Payments      
Percentage that vests during the period 50.00%    
Inducement Awards Outside of the 2019 Inducement Plan | Non-statutory option | First anniversary of FDA approval      
Share-Based Payments      
Percentage that vests during the period 50.00%    
Inducement Awards Outside of the 2019 Inducement Plan | Restricted Stock Units ("RSUs")      
Share-Based Payments      
Options exercise price (in dollars per share)   $ 3.53  
Inducement Awards Outside of the 2019 Inducement Plan | Restricted Stock Units ("RSUs") | Chief Executive Officer      
Share-Based Payments      
Options granted during the period 150,000