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Organization and Business Activities (Details) - USD ($) $ in Millions	1 Months Ended		14 Months Ended
	May 10, 2019	Apr. 30, 2019	May 10, 2019	Mar. 31, 2019	Dec. 31, 2018	Mar. 31, 2018
Liquidity
Cash, cash equivalents and short-term investments				$ 91.3
ATM Agreement \| At-the-market offering \| Ordinary Shares
Liquidity
Proceeds from at-the-market facility	$ 3.5		$ 37.8
Number of shares issued			10,316,190
Net proceeds from sale of stock			$ 36.9
ATM Agreement \| Cantor Fitzgerald and Co. \| At-the-market offering \| Ordinary Shares
Liquidity
Maximum aggregate gross proceeds under the sales agreement						$ 50.0
License Agreement \| Collaboration revenue - upfront payment \| Sunovion Pharmaceutics Canada, Inc.
Liquidity
Proceeds received from Sunovion license		$ 1.0
Loan Agreement \| Term loan
Liquidity
Maximum borrowing capacity					$ 75.0
Loan Agreement \| Term loan \| Initial Advance
Liquidity
Maximum borrowing capacity					$ 25.0
Loan Agreement \| Term loan \| Additional term loan advances
Liquidity
Maximum borrowing capacity				$ 50.0