Revenue (Details) - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2018	Mar. 31, 2017
Revenue
Revenue	$ 7,551	$ 1,678
Collaboration revenue
Revenue
Revenue	6,500
Upfront payment received \| Sinovant Sciences, LTD
Revenue
Revenue	5,000
Variable consideration \| Sinovant Sciences, LTD
Revenue
Revenue	1,500
Research premium
Revenue
Revenue	770	1,505
Government grants
Revenue
Revenue	$ 281	147
Grants from WWFF
Revenue
Revenue		$ 26

Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

Name:	us-gaap_Revenues
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration