5.Revenue

	Three Months Ended March 31,
(in thousands)	2017		2018
Collaboration revenue	$	—	$	6,500
Research premium	1,505		770
Government grants	147		281
Grants from WWFF	26		—

Total	$	1,678	$	7,551

The collaboration revenue for the three months ended March 31, 2018 reflects the amounts recorded from the Sinovant License Agreement (see Note 9) and includes the $5.0 million non-refundable upfront payment received as consideration for entering into the license agreement with Sinovant as well as $1.5 million of variable consideration related a future milestone payment that the Company believes is probable to be met and received.